![[Leu15]-Gastrin I (human)](https://file.medchemexpress.com/product_pic/hy-p2671.gif "Click to View [Leu15]-Gastrin I (human) Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
83 Results for "
Cholecystokinin Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (83)
83 Results for "Cholecystokinin Receptor" in MCE Product Catalog:
148
148 Publications Verification
Cat. No.: HY-A0190
CAS No.: 17650-98-5
Synonyms: Ceruletide; Cerulein; FI-6934
Category:
Cardiovascular Disease Alkaloids Animals Disease Research Fields Endocrinology Indole Alkaloids
Target:
18
18 Cited Publications
Cat. No.: HY-P1097
CAS No.: 10047-33-3
Target:
Research Areas:
6
6 Cited Publications
Synonyms: L-364,718; MK-329
Target:
Research Areas:
Devazepide (L-364,718) is a potent, competitive, selective and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor, with IC50s of 81 pM, 45 pM and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively. Devazepide (L-364,718) is effective for gastrointestinal disorders .
4
Target:
Research Areas:
Loxiglumide is a cholecystokinin (CCK-1) receptor antagonist.
2
2 Cited Publications
Target:
Research Areas:
L-365260 is an orally active and selective antagonist of non-peptide gastrin and brain cholecystokinin receptor (CCK-B), with Kis of 1.9 nM and 2.0 nM, respectively. L-365260 interacts in a stereoselective and competitive manner with guinea pig stomach gastrin and brain CCK receptors. L-365260 can enhance Morphine analgesia and prevents Morphine tolerance .
2
2 Cited Publications
Target:
Research Areas:
YM022 is a highly potent, selective and orally active gastrin/cholecystokinin (CCK)-B receptor (CCK-BR) antagonist. YM022 shows the Ki values of 68 pM and 63 nM for CCK-B and CCK-A receptor, respectively . YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo .
2
2 Cited Publications
Cat. No.: HY-106840A
Purity: 99.75%
Target:
Research Areas:
L-365260 hemihydrate is an orally active and selective antagonist of non-peptide gastrin and brain cholecystokinin receptor (CCK-B), with Kis of 1.9 nM and 2.0 nM, respectively. L-365260 hemihydrate interacts in a stereoselective and competitive manner with guinea pig stomach gastrin and brain CCK receptors .
1
1 Cited Publications
Cat. No.: HY-P2671
CAS No.: 39024-57-2
Target:
Research Areas:
1
Target:
Research Areas:
1
Target:
Research Areas:
Proglumide is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist. Proglumide selective blocks CCK’s effects in the central nervous system (CNS). Proglumide has ability to inhibit gastric secretion and to protect the gastroduodenal mucosa. Proglumide also has antiepileptic and antioxidant activities .
1
1 Cited Publications
Synonyms: Cholecystokinin tetrapeptide; CCK-4
Target:
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
Proglumide sodium is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist. Proglumide sodium selective blocks CCK’s effects in the central nervous system (CNS). Proglumide sodium has ability to inhibit gastric secretion and to protect the gastroduodenal mucosa. Proglumide sodium also has antiepileptic and antioxidant activities .
Cat. No.: HY-B1439B
CAS No.: 1021868-76-7
Synonyms: CR-1409 sodium
Target:
Research Areas:
Lorglumide sodium salt (CR-1409 sodium salt) is a potent cholecystokinin (CCK) receptor antagonist .
Target:
Research Areas:
SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist.
Research Areas:
Dexloxiglumide is an orally active and selective cholecystokinin type A (CCKA) receptor antagonist. Dexloxiglumide is the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8). Dexloxiglumide exhibits moderate Caco-2 permeability that is polarized, concentration dependent, and pH dependent. Dexloxiglumide increases MRP1-substrate fluorescein uptake. Dexloxiglumide can be studied in research for gastrointestinal diseases and tumors .
Cat. No.: HY-U00360
CAS No.: 168161-71-5
Synonyms: (Rac)-Netazepide; (Rac)-YF 476; (Rac)-YM-220
Target:
Research Areas:
(Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.
Target:
Research Areas:
LY 225910 is a selective antagonist for cholecystokinin receptor (CCK2 receptor), which affects the excitatory response to morphine, and leads to morphine sensitization .
Synonyms: SR 27897
Target:
Research Areas:
Lintitript (SR 27897) is a highly potent, selective, orally active, competitive and non-peptide cholecystokinin (CCK1) receptor antagonist with an EC50 of 6 nM and a Ki of 0.2 nM. Lintitript displays > 33-fold selectivity more selective for CCK1 than CCK2 receptors (EC50 value of 200 nM). Lintitript increases plasma concentration of leptin and food intake as well as plasma concentration of insulin .
Cat. No.: HY-177506
CAS No.: 158459-39-3
Target:
Research Areas:
FE100726 (Compound 39) is a Cholecystokinin 2 (CCK2) receptor agonist. FE100726 has a superior binding capacity on CCK2 receptor. FE100726 can induce gastric acid secretion in anaesthetized rat models. FE100726 can be used for diabetes research .
Cat. No.: HY-111313
CAS No.: 844645-08-5
Target:
Research Areas:
JNJ-26070109 is a high-affinity, competitive, orally bioactive, and selective cholecystokinin 2 (CCK2) receptor antagonist with good pharmacokinetic properties, with pKis of 8.49, 7.99, and 7.70 for human, rat, and dog CCK2 receptors, respectively. The dual function of CCK2 receptors in regulating gastric acid secretion and growth of the gastrointestinal mucosa make this an attractive and novel target for the research of gastroesophageal reflux disease .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
