56 Results for "

Codonopsis ovata Benth.

" in MedChemExpress (MCE) Product Catalog:
Products (56)

56 Results for "Codonopsis ovata Benth." in MCE Product Catalog:

9
9 Publications Verification
Art. -Nr.: HY-N2897
CAS. Nr.: 480-20-6
Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic agents .
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7
7 Cited Publications
Art. -Nr.: HY-N0792
CAS. Nr.: 548-77-6
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
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4
4 Cited Publications
Art. -Nr.: HY-N0327
CAS. Nr.: 129277-38-9
Lobetyolin, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism . Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1
1 Cited Publications
Art. -Nr.: HY-N6850
CAS. Nr.: 26020-14-4
Calenduloside E is a pentacyclic triterpenoid saponin that can be extracted from the bark and roots of Aralia ovata, and has anti-inflammatory and anti-apoptotic activities. Calenduloside E alleviates atherosclerosis by regulating macrophage polarization, improves mitochondrial function by regulating the AMPK-SIRT3 pathway, and alleviates acute liver injury. In addition, Calenduloside E promotes the interaction between L-type calcium channels and Bcl-2 related apoptosis genes, inhibits calcium overload, and alleviates myocardial ischemia/reperfusion injury. Calenduloside E also improves non-alcoholic fatty liver disease by regulating heat shock-dependent pathways, and inhibits ROS mediated JAK1-STAT3 pathways to reduce cellular inflammatory responses .
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Art. -Nr.: HY-N1399
CAS. Nr.: 531-28-2
Androsin is an active compound isolated from Picrorhiza Kurroa Royle ex Benth. Androsin activates AMPKα/PI3K/Beclin1/LC3 signaling pathway, inhibits SREBP1c/FASN signaling pathway. Androsin can be used in research of asthma and non-alcoholic fatty liver disease (NAFLD). Androsin is orally active .
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Art. -Nr.: HY-N9317
CAS. Nr.: 117278-74-7
Tangshenoside I, isolated from the roots of Codonopsis lanceolata, exhibits weak α-glucosidase inhibitory activities in vitro with an IC50 of 1.4 mM .
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Art. -Nr.: HY-N2138
CAS. Nr.: 152580-79-5
Buddlejasaponin IVb (Compound 2), a triterpene saponin isolated from Clinopodium chinense (Benth.) O. Kuntze, Compound 2 has hemostasis efficacy, shortens thrombin time (TT) by 20.6 % .
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Art. -Nr.: HY-N4031
CAS. Nr.: 82375-29-9
Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
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Art. -Nr.: HY-N8344
CAS. Nr.: 521-62-0
Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .
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Art. -Nr.: HY-W540600
CAS. Nr.: 53850-34-3
Thaumatins is a protein, which can be purified from the fruit of Thaumatococcus daniellii Benth. Thaumatins is 100,000 times sweeter than sucrose on a molar basis .
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Art. -Nr.: HY-124031
CAS. Nr.: 142451-48-7
Reinheit:  98.98%
Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research .
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Art. -Nr.: HY-N3706
CAS. Nr.: 15297-92-4
Target:  

Fungal

Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
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Art. -Nr.: HY-N7591
CAS. Nr.: 1393922-01-4
Millepachine is a bioactive natural chalcone from Chinese herbal medicine Millettia pachycarpa Benth, exhibits strong antitumor effects against numerous human cancer cells both in vitro and in vivo .
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Art. -Nr.: HY-N11554
CAS. Nr.: 26989-20-8
(-)-Codonopsine is an alkaloid with antibacterial activity. (-)-Codonopsine can be used in research related to Staphylococcus aureus and Escherichia coli infections .
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Art. -Nr.: HY-N16598
CAS. Nr.: 887140-17-2
4''-O-Methylcatalposide (compound 7) is a glycoside from the stem bark of Catalpa ovata. 4''-O-Methylcatalposide exhibits peroxynitrite (ONOO )-scavenging activity with an IC50 of 36.4 μM. 4''-O-Methylcatalposide can be used for anti-inflammatory research .
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Art. -Nr.: HY-W193398
CAS. Nr.: 62141-38-2
Target:  

Monoamine Oxidase

Forschungsgebiete:  

Cardiovascular Disease

N-2-Cyclohexylethyl-N-methylamine is an amine from A.ridigula Benth for a reduction of monoamine oxidase (MAO) activity .
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Art. -Nr.: HY-N5125
CAS. Nr.: 6170-06-5
2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity .
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Art. -Nr.: HY-N0792R
CAS. Nr.: 548-77-6
Tectorigenin (Standard) is the analytical standard of Tectorigenin. This product is intended for research and analytical applications. Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
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Art. -Nr.: HY-121211
CAS. Nr.: 477-86-1
Reinheit:  94.99%
Target:  

Parasite

Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of Plasmodium falciparum with an IC50 value of 12.92 μg/mL. Digitolutein can be used for the research of infection .
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Art. -Nr.: HY-N12959
CAS. Nr.: 927406-46-0
Synonyms: DDR
5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone (DDR) is an anticancer agent that can be extracted from Indigofera ovata. 5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone can inhibit the PI3K/AKT and NF-кB pathways, inhibit the invasion and migration of cancer cells, and has anticancer activity .
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