5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone
5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone (DDR) is an anticancer agent that can be extracted from Indigofera ovata. 5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone can inhibit the PI3K/AKT and NF-кB pathways, inhibit the invasion and migration of cancer cells, and has anticancer activity.
For research use only. We do not sell to patients.
- CAS No.: 927406-46-0
- Formula: C23H24O11
- Molecular Weight:476.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 927406-46-0
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Molecular Weight 476.43
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Formula C23H24O11
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SMILES
COC1=C2C(C(C=C(C3=CC=C(C=C3)O)O2)=O)=C(C(OC)=C1O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)O
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Synonyms
DDR
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell migration
Cell migration is a method that plays an important role in wound healing, cell differentiation, embryonic development, etc.
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Cell invasion
Cell invasion is the ability of cells to migrate from one area to another via the extracellular matrix. Cell invasion is the response of normal and cancer cells to chemical and mechanical stimuli. Before migrating to a new region, the extracellular matrix is degraded by proteases within the cell. Cell invasion often occurs during wound repair, vascularization and inflammation, abnormal tissue invasion, and tumor cell metastasis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone Related Classifications
HY-N12959 Related Classifications
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