1 Result for "

Computational simulations

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Computational simulations" in MCE Product Catalog:

Cat. No.: HY-175303
CAS No.: 185522-92-3
Target:  

Xanthine Oxidase

Research Areas:  

Metabolic Disease

Xanthine oxidase-IN-17 is a potent xanthine oxidase (XOD) inhibitor with an IC50 of 298 nM and a Ki of 167 nM. Xanthine oxidase-IN-17 decreases the formation of O radical by inhibiting the catalytic activity of XOD to diminish the production of uric acid. Xanthine oxidase-IN-17 shows no cytotoxicity in AML-12 hepatocytes, while suppressing uric acid production. Xanthine oxidase-IN-17 can be used for the studies of hyperuricemia and subsequently to gout .
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