Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Curcuma longa
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Curcuma longa" in MCE Product Catalog:
2
1
Category:
Zingiberaceae Extract Ketones, Aldehydes, Acids Plants Curcuma longa Disease Research Fields Inflammation/Immunology
Target:
Synonyms: DiMC; CHC 004; Di-O-methylcurcumin
Target:
Androgen Receptor Reactive Oxygen Species (ROS) Apoptosis NF-κB CDK Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase PI3K Akt AMPK ERK JNK
Research Areas:
Dimethoxycurcumin (DiMC) is a curcuminoid compound found in Curcuma longa. Dimethoxycurcumin is also an orally active thioredoxin reductase inhibitor (IC50 = 5.4 μM) and androgen receptor antagonist. Dimethoxycurcumin inhibits thioredoxin reductase, leading to oxidized thioredoxin accumulation, ROS production, DNA damage, glutathione depletion, mitochondrial membrane potential decrease, ATP depletion, S phase arrest, and apoptosis. Dimethoxycurcumin inhibits NF-κB, NADPH oxidase subunits, ATP synthase subunits, CDK4, cyclin-D1, FASN, ACC, and the IRS2-PI3K-Akt pathway, while activating AMPK, ERK, and JNK. Dimethoxycurcumin can be used for research on cancer, arsenic-induced hepatotoxicity, and tuberculosis .
Cat. No.: HY-N0893R
CAS No.: 36062-04-1
Synonyms: HZIV 81-2 (Standard)
Cat. No.: HY-N16650
CAS No.: 2871811-08-2
Target:
Cat. No.: HY-N8047
CAS No.: 79559-61-8
Category:
Target:
Cat. No.: HY-N21256
Category:
Target:
Cat. No.: HY-N18668
CAS No.: 84775-52-0
Cat. No.: HY-N8953
CAS No.: 127214-86-2
Target:
Cat. No.: HY-N0894B
CAS No.: 112494-41-4
Synonyms: (3S,5S)-Hexahydrobisdemethoxycurcumin
Target:
Cat. No.: HY-N0996
CAS No.: 1083195-05-4
Category:
Zingiberaceae Extract Other Diseases Phenols Polyphenols Plants Curcuma longa Disease Research Fields
Target:
Cat. No.: HY-N9018
CAS No.: 170380-68-4
Target:
Cat. No.: HY-N6703S
Synonyms: (+)-ar-Turmerone-d3
Cat. No.: HY-N9019
CAS No.: 170380-69-5
Target:
Cat. No.: HY-100977S
CAS No.: 3006902-95-7
Synonyms: DiMC-d6; CHC 004-d6; Di-O-methylcurcumin-d6
Target:
Isotope-Labeled Compounds Androgen Receptor Reactive Oxygen Species (ROS) Apoptosis NF-κB CDK Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase PI3K Akt AMPK ERK JNK
Research Areas:
Dimethoxycurcumin-d6 (DiMC-d6; CHC 004-d6; Di-O-methylcurcumin-d6) is the deuterated-labeled Dimethoxycurcumin (HY-100977). Dimethoxycurcumin (DiMC) is a curcuminoid compound found in Curcuma longa. Dimethoxycurcumin is also an orally active thioredoxin reductase inhibitor (IC50 = 5.4 μM) and androgen receptor antagonist. Dimethoxycurcumin inhibits thioredoxin reductase, leading to oxidized thioredoxin accumulation, ROS production, DNA damage, glutathione depletion, mitochondrial membrane potential decrease, ATP depletion, S phase arrest, and apoptosis. Dimethoxycurcumin inhibits NF-κB, NADPH oxidase subunits, ATP synthase subunits, CDK4, cyclin-D1, FASN, ACC, and the IRS2-PI3K-Akt pathway, while activating AMPK, ERK, and JNK. Dimethoxycurcumin can be used for research on cancer, arsenic-induced hepatotoxicity, and tuberculosis .
Target:
Cat. No.: HY-N12558
CAS No.: 20303-60-0
Category:
Zingiberaceae Extract Terpenoids Sesquiterpenes Curcuma aromatica Salisb. cv. Wenyujin Plants
Target:
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
