532-65-0
Chemical Structure
ar-Turmerone
Synonym(s): (+)-ar-Turmerone
- CAS No.: 532-65-0
- Formula:C15H20O
- Molecular Weight:216.32
IUPAC Name: (S)-2-methyl-6-(p-tolyl)hept-2-en-4-one
InChIKey: NAAJVHHFAXWBOK-ZDUSSCGKSA-N
SMILES: CC1=CC=C(C=C1)[C@H](CC(/C=C(C)\C)=O)C
Biological Activity: ar-Turmerone ((+)-ar-Turmerone) is an orally active and major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities. ar-Turmerone induces apoptosis in U937 cells. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation in vitro and in vivo, and can be used for various neurologic disorders study[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ar-Turmerone | 99.00% | ar-Turmerone ((+)-ar-Turmerone) is an orally active and major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities. ar-Turmerone induces apoptosis in U937 cells. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation in vitro and in vivo, and can be used for various neurologic disorders study. | ||||||||||||||||||||
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ar-Turmerone-d3 | ar-Turmerone-d3 is the deuterium labeled ar-Turmerone. ar-Turmerone ((+)-ar-Turmerone) is an orally active and major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities. ar-Turmerone induces apoptosis in U937 cells. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation in vitro and in vivo, and can be used for various neurologic disorders study. | |||||||||||||||||||||
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Similarity Score 1.00
HY-N6703A(R)-ar-Turmerone -
Similarity Score 0.86
HY-N170956-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one -
Similarity Score 0.80
HY-N9239Turmeronol A -
Similarity Score 0.79
HY-N92496-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one -
Similarity Score 0.79
HY-N133088-Hydroxy-ar-turmerone -
Similarity Score 0.78
HY-N16786Turmeronol B -
Similarity Score 0.78
HY-N16722(S)-ar-Turmerol -
Similarity Score 0.75
HY-N877611-Hydroxybisabola-1,3,5-trien-9-one -
Similarity Score 0.68
HY-112657Xanthorrhizol -
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References
- [1]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31. [Content Brief]
- [2]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20. [Content Brief]
- [3]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100. [Content Brief]
- [4]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24. [Content Brief]
- [5]. Zhou W, et al. Structural optimization of naturally derived Ar-turmerone, as novel neuroinflammation suppressors effective in an Alzheimer mouse model. Bioorg Med Chem. 2025 Jan 1;117:118014. [Content Brief]