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DPEP3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) SARS-CoV (1)
By Research Areas:	Cancer (2) Endocrinology (1) Infection (1) Inflammation/Immunology (1)

Inhibitors & Agonists

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Inhibitory Antibodies

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Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99506

Tamrintamab SC-003 mAb; SC-Mab003; SC34.28ss1	ADC Antibody	Cancer
Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or *MBD3). DPEP3* is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research .

HY-P11879

LSALT peptide	SARS-CoV	Infection Inflammation/Immunology Endocrinology
LSALT peptide is a selective *DPEP-1* inhibitor with selectivity over *DPEP2*/3. LSALT peptide inhibits neutrophil and monocyte/macrophage recruitment, inflammation, and tissue injury. LSALT peptide reduces kidney damage, improves survival in murine sepsis and endotoxemia models. LSALT peptide can be used for the research of COVID-19, sepsis, acute respiratory distress syndrome, and acute kidney injury ^[3].

Cat. No.	Product Name	Target	Research Area

HY-P11879

LSALT peptide	SARS-CoV	Infection Inflammation/Immunology Endocrinology
LSALT peptide is a selective *DPEP-1* inhibitor with selectivity over *DPEP2*/3. LSALT peptide inhibits neutrophil and monocyte/macrophage recruitment, inflammation, and tissue injury. LSALT peptide reduces kidney damage, improves survival in murine sepsis and endotoxemia models. LSALT peptide can be used for the research of COVID-19, sepsis, acute respiratory distress syndrome, and acute kidney injury ^[3].

Cat. No.	Product Name	Target	Research Area	Image

HY-P99506

Tamrintamab SC-003 mAb; SC-Mab003; SC34.28ss1	ADC Antibody	Cancer
Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or *MBD3). DPEP3* is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research .

HY-P992093

Pintumomab	Inhibitory Antibodies	Cancer
Pintumomab is an anti-human monoclonal antibody targeting *DPEP3*.

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704108

	DPEP3 Protein, Human (HEK293, His) UNQ834; PRO1772; Dipeptidase 3; DPEP3	Human	HEK293
	DPEP3 Protein, Human (HEK293, His) is the recombinant human-derived DPEP3 protein, expressed by HEK293, with C-10*His tag.

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Host:	Rabbit (3)
Reactivity:	Human (3)
Application:	IHC-P (3) IP (1) WB (1)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

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HY-P86265

	DPEP3 Antibody (YA5957) DPEP3; UNQ834/PRO1772; Dipeptidase 3;	WB, IHC-P, IP	Human
	DPEP3 Antibody (YA5957) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPEP3.

HY-P81490

	DPEP3 Antibody (YA1235) DPEP3; UNQ834/PRO1772; Dipeptidase 3	IHC-P	Human
	DPEP3 Antibody (YA1235) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPEP3.

HY-P81490A

	DPEP3 Antibody (YA1235)(PBS only) DPEP3; UNQ834/PRO1772; Dipeptidase 3	IHC-P	Human
	DPEP3 Antibody (YA1235) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPEP3.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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