2 Results for "

EC145

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "EC145" in MCE Product Catalog:

Cat. No.: HY-129880
CAS No.: 55383-37-4
Synonyms: Deacetylvinblastine hydrazide; DAVLBH
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Desacetylvinblastine hydrazide (Deacetylvinblastine hydrazide; DAVLBH) is an active component of EC145, a folate-targeted drug conjugate. Desacetylvinblastine hydrazide interferes with the formation of the mitotic spindle, and thus inhibits cell division and leads to cell death. Desacetylvinblastine hydrazide exhibits antitumor activity against folate receptor (FR)-positive tumor .
loading...
    loading...
Cat. No.: HY-P2631
CAS No.: 742091-99-2
Target:  

Folate Receptor (FR)

Research Areas:  

Others

EC119 consists of Pteroic acid-gGlu-Asp-Arg-Asp-Asp-Cys, which is the folate–peptide moiety found within both the EC140 and EC145 structures .
loading...
    loading...