6 Results for "

EC5026

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "EC5026" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-N0049
CAS No.: 475-83-2
Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.
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1
1 Cited Publications
Cat. No.: HY-135653
CAS No.: 1809885-32-2
Purity:  98.13%
Synonyms: BPN-19186
Target:  

Epoxide Hydrolase

Research Areas:  

Neurological Disease

EC5026 (BPN-19186) is a first-in-class, non-opioid and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 shows efficacy for inflammatory and neuropathic pain .
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Cat. No.: HY-135653A
CAS No.: 1809885-55-9
Purity:  98.25%
Synonyms: (Rac)-BPN-19186
Target:  

Epoxide Hydrolase

Research Areas:  

Neurological Disease

(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) .
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Cat. No.: HY-138879
CAS No.: 357425-02-6
Purity:  98.24%
Target:  

nAChR

Research Areas:  

Neurological Disease

CP-601927 is a selective α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist (Ki=1.2 nM; EC50=2.6 μM). CP-601927 shows good brain penetration and antidepressant-like properties .
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Cat. No.: HY-162120
Target:  

Epoxide Hydrolase

Research Areas:  

Infection

FZQ-21 (Compound 70P) is a soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 4 nM. FZQ-21 exhibits equal IC50 (1.5 nM) on inhibiting human sEH as EC5026 (HY-135653) (1.7 nM). FZQ-21 can be used for research of sepsis .
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Cat. No.: HY-N0049R
CAS No.: 475-83-2
Nuciferine (Standard) is the analytical standard of Nuciferine. This product is intended for research and analytical applications. Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.
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