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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
ERD 1233
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "ERD 1233" in MCE Product Catalog:
Cat. No.: HY-169367
Target:
Research Areas:
ERD-1233 is an orally active ERα PROTAC degrader with a DC50 of 0.9 nM. ERD-1233 exhibits plasma stability and microsomal stability across multiple species, and shows no significant inhibitory effect on major cytochrome P450 subtypes and hERG channels. ERD-1233 inhibits tumor growth and degrades ERα protein levels in xenograft tumor models, with favorable biosafety. ERD-1233 can be used in breast cancer-related research .
Cat. No.: HY-201580
CAS No.: 2229713-97-5
Research Areas:
ER ligand-8 is an ER (Estrogen Receptor/ERR) ligand that can be used to synthesize the PROTAC molecule ERD-1233 (HY-169367) .
Cat. No.: HY-172067
CAS No.: 3026011-20-8
Research Areas:
ER ligand-9 is a conjugate of an estrogen receptor (Estrogen Receptor/ERR) and a linker, which can be used to synthesize PROTAC ERD-1233 (HY-169367) .
Cat. No.: HY-W889109
CAS No.: 3026011-77-5
Target:
Research Areas:
3-(Dimethoxymethyl)-1-oxa-8-azaspiro[4.5]decane is a PROTAC linker that can be used to synthesize ERD-1233 (HY-169367) .
Cat. No.: HY-W1009348
CAS No.: 3026009-09-3
Target:
Research Areas:
RR-11055 (Compound 8) is a ligand for E3 ligase, that exhibits an affinity with cereblon with Ki of 0.38 μM. RR-11055 can be used for synthesis of PROTAC Degrader ERD-1233 (HY-169367) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
