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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Edelfosine
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Edelfosine" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: ET-18-OCH3
Target:
Forschungsgebiete:
Edelfosine (ET-18-OCH3) is an orally active lipid raft modulator and apoptosis inducer that alters membrane fluidity and preferentially inserts into tumor cell membranes. Edelfosine recruits death receptor ligands (FasL/CD95L, TRAIL) and Bid to lipid rafts to form death-inducing signaling complexes, thereby initiating mitochondria-dependent apoptosis and inducing cytochrome c release. Edelfosine also exerts anti-inflammatory effects, promotes L-Selectin shedding, and causes no gastrointestinal or organ toxicity. In addition, Edelfosine inhibits nucleic acid and protein synthesis in Leishmania donovani and exhibits antiproliferative activity. Edelfosine can be used in research on multiple myeloma, inflammatory bowel diseases (such as ulcerative colitis and Crohn's disease), and visceral leishmaniasis .
Art. -Nr.: HY-108610C
CAS. Nr.: 83542-43-2
Synonyms: (S)-ET-18-OCH3
(S)-Edelfosine ((S)-ET-18-OCH3) is the (S)-enantiomer of Edelfosine (ET-18-OCH3) (HY-108610C). Edelfosine is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor .
Art. -Nr.: HY-108610R
CAS. Nr.: 77286-66-9
Synonyms: (R)-ET-18-OCH3 (Standard)
Target:
(R)-Edelfosine (Standard) is the analytical standard of (R)-Edelfosine (HY-108610). This product is intended for research and analytical applications. (R)-Edelfosine ((R)-ET-18-OCH3) is a ether lipid analog with anti-HIV and antineoplastic activity .
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