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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Fingolimod
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Fingolimod" in MCE Product Catalog:
78
78 Publications Verification
Synonyms: FTY720
Target:
Research Areas:
Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant .
78
78 Publications Verification
Synonyms: FTY720 free base
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant .
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1 Cited Publications
Synonyms: FTY720 phosphate
Target:
Research Areas:
Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases .
Cat. No.: HY-16734A
CAS No.: 942398-84-7
Synonyms: MT-1303 hydrochloride
Target:
Research Areas:
Amiselimod (MT-1303) hydrochloride is converted to its active metabolite Amiselimod phosphate by sphingosine kinases in vivo. Amiselimod hydrochloride is an orally active and high selectivity sphingosine 1-phosphate receptor-1 (S1P1) agonist, designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. Amiselimod hydrochloride inhibits chronic colitis via inhibiting infiltration of colitogenic Th1 and Th17 cells into the colon. Amiselimod hydrochloride inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. Amiselimod hydrochloride is promising for research of autoimmune diseases .
Cat. No.: HY-11063R
CAS No.: 162359-55-9
Synonyms: FTY720 free base (Standard)
Target:
Research Areas:
Fingolimod (Standard) is the analytical standard of Fingolimod. This product is intended for research and analytical applications. Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant .
Synonyms: FTY720 free based-d4
Cat. No.: HY-12005R
CAS No.: 162359-56-0
Synonyms: FTY720 (Standard)
Target:
Research Areas:
Fingolimod (hydrochloride) (Standard) is the analytical standard of Fingolimod (hydrochloride). This product is intended for research and analytical applications. Fingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1-phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator .
Cat. No.: HY-135284
CAS No.: 1604816-11-6
Target:
Research Areas:
FTY720-Mitoxy is a fingolimod hydrochloride (HY-12005) derivative with neuroprotective and PP2A activating activities. FTY720-Mitoxy has the property of targeting mitochondria. In addition, FTY720-Mitoxy protects neurons by reducing inflammatory responses and is used in the study of neurodegenerative diseases such as Parkinson's disease .
Cat. No.: HY-15381R
CAS No.: 402615-91-2
Synonyms: FTY720 phosphate (Standard)
Target:
Research Areas:
Fingolimod phosphate (Standard) is the analytical standard of Fingolimod phosphate. This product is intended for research and analytical applications. Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases .
Cat. No.: HY-143959S
Cat. No.: HY-16734
CAS No.: 942399-20-4
Synonyms: MT-1303
Target:
Research Areas:
Amiselimod (MT-1303) is converted to its active metabolite Amiselimod phosphate by sphingosine kinases in vivo. Amiselimod is an orally active and high selectivity sphingosine 1-phosphate receptor-1 (S1P1) agonist, designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. Amiselimod inhibits chronic colitis via inhibiting infiltration of colitogenic Th1 and Th17 cells into the colon. Amiselimod inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. Amiselimodis promising for research of autoimmune diseases .
Synonyms: FTY720-d4
Cat. No.: HY-15381S
CAS No.: 1794828-93-5
Synonyms: FTY720 phosphate-d4
Cat. No.: HY-108399
CAS No.: 162358-08-9
Target:
Research Areas:
Fingolimod impurity 3 is an impurity of Fingolimod (HY-11063).
Cat. No.: HY-181455
CAS No.: 2309930-88-7
Target:
Research Areas:
rel-FTY720 phenoxy-biotin hydrochloride is a chemical probe designed based on the structure of Fingolimod (HY-12005), which incorporates a phenoxy group capable of specific click chemistry reactions and is conjugated with a biotin tag .
Cat. No.: HY-12898
CAS No.: 1142015-13-1
Target:
Research Areas:
(S)-FTY-720 Vinylphosphonate is a chiral phosphonate analogue of Fingolimod (HY-11063). (S)-FTY-720 Vinylphosphonate can activate the S1P1 receptor with an EC50 value of 75 nM. (S)-FTY-720 Vinylphosphonate can significantly inhibit Camptothecin (HY-16560)-induced apoptosis in IEC-6 cells. (S)-FTY-720 Vinylphosphonate is applicable for the research of autoimmune diseases .
Cat. No.: HY-108399R
CAS No.: 162358-08-9
Target:
Diethyl 2-(acetamido)-2-(2-(4-octylphenyl)ethyl)propanedioate (Standard) is the analytical standard of Diethyl 2-(acetamido)-2-(2-(4-octylphenyl)ethyl)propanedioate. This product is intended for research and analytical applications.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
