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Fur

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Drug Derivative (1) Drug Intermediate (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W088190

Dicyclohexyl ketone Cyclohexyl ketone	Drug Intermediate Biochemical Assay Reagents	Others
Dicyclohexyl ketone (Cyclohexyl ketone) is a toxic compound that causes toxic effects in rats at high doses, including death, decreased activity, staining of the fur on the lower body, reddening of the tears, and reproductive and developmental effects.

HY-N15577

Antiproliferative agent-69	Drug Derivative	Cancer
Antiproliferative agent-69 (Compound 1) is a prenylated kaempferol derivative found in the fresh bud’s fur of Platanus acerifolia. Antiproliferative agent-69 shows significant antiproliferative effects against human breast cancer cells (MCF-7) and human hepatocellular carcinoma cells (Hep-G2) with IC₅₀ values of 38.2 μM and 39.5 μM, respectively. Antiproliferative agent-69 is promising for research of breast cancer and liver cancer .

HY-RS05148

FURIN Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FURIN Human Pre-designed siRNA Set A contains three designed siRNAs for FURIN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FURIN Human Pre-designed siRNA Set A FURIN Human Pre-designed siRNA Set A

HY-RS19197

Furin Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Furin Mouse Pre-designed siRNA Set A contains three designed siRNAs for Furin gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Furin Mouse Pre-designed siRNA Set A Furin Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N15577

Antiproliferative agent-69	Flavonols Platanus acerifolia Aiton) Willd. Flavonoids Platanaceae Plants Source Classification	Drug Derivative
Antiproliferative agent-69 (Compound 1) is a prenylated kaempferol derivative found in the fresh bud’s fur of Platanus acerifolia. Antiproliferative agent-69 shows significant antiproliferative effects against human breast cancer cells (MCF-7) and human hepatocellular carcinoma cells (Hep-G2) with IC₅₀ values of 38.2 μM and 39.5 μM, respectively. Antiproliferative agent-69 is promising for research of breast cancer and liver cancer .

Species:	Human (2) Mouse (1)
Tag:	His (3)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78747

	Furin/PCSK3 Protein, Human (HEK293, His) 1 Publications Verification FurIN; Fur; PACE; PCSK3; SPC1	Human	HEK293
	Furin/PCSK3 protein is a ubiquitous endoprotease in the constitutive secretory pathway that efficiently cleaves the RX(K/R)R consensus motif. Its versatility is evident in processing TGFB1 (essential for TGF-β-1 activation) and converting the brain natriuretic factor prohormone into active BNP(1-32). Furin/PCSK3 Protein, Human (HEK293, His) is the recombinant human-derived Furin/PCSK3 protein, expressed by HEK293 , with C-His, C-6*His labeled tag.

HY-P79228

	Furin/PCSK3 Protein, Mouse (HEK293, His) Furin; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACE; Prohormone convertase 3; Fur; Pcsk3	Mouse	HEK293
	Furin/PCSK3 protein is an endoprotease with RX(K/R)R cleavage activity and is widely expressed in the constitutive secretory pathway.It plays a crucial role in processing various substrates, including TGFB1, and activating TGF-β-1.Furin/PCSK3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Furin/PCSK3 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P71417

	UPRT Protein, Human (His) Uracil phosphoribosyltransferase homolog; UPP; Fur1; UPRT	Human	E. coli
	Uracil phosphoribosyltransferase homolog (UPRT) catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP) which is an important part of nucleotide metabolism. UPRT localizes to the nucleus and cytoplasm, and is a potential target for rational design of drugs to treat parasitic infections and cancer. UPRT Protein, Human (His) is the recombinant human-derived UPRT protein, expressed by E. coli , with N-6*His labeled tag.

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Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (3) Rat (3) Mouse (3)
Application:	IHC-P (3) ICC/IF (3) WB (1)
Isotype:	IgG (1) IgG2a (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

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HY-P81696

	Furin Antibody (YA1441) Fur; FurIN; PACE; PCSK3; SPC1	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Furin Antibody (YA1441) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Furin.

HY-P88640

	UPRT Antibody (YA8324) Fur1; UPP	IHC-P, ICC/IF	Human, Mouse, Rat
	UPRT Antibody (YA8324) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UPRT.

HY-P88640A

	UPRT Antibody (YA8324)(PBS only) Fur1; UPP	IHC-P, ICC/IF	Human, Mouse, Rat
	UPRT Antibody (YA8324) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UPRT.

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HY-RS05148

FURIN Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
FURIN Human Pre-designed siRNA Set A contains three designed siRNAs for FURIN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS19197

Furin Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Furin Mouse Pre-designed siRNA Set A contains three designed siRNAs for Furin gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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