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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
GPR39
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "GPR39" in MCE Product Catalog:
5
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TC-G-1008 (GPR39-C3) is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively.
Cat. No.: HY-137255
CAS No.: 64936-83-0
Synonyms: 3-Sulfotaurolithocholic acid disodium
Synonyms: Sulfolithocholic acid disodium; LCAS disodium
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TM-N1324 is an agonist of G-Protein-Coupled Receptor 39 (GPR39) with EC50s of 9 nM/5 nM in the presence of Zn 2+, and 280 nM/180 nM in the absence of Zn 2+ for human/murine GPR39.
Cat. No.: HY-W587430
CAS No.: 64936-82-9
Synonyms: Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium
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Glycolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 47.9 and 66.8 μM (absence of Zn 2+) and 8 and 8.7 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Glycolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Glycolithocholic acid 3-sulfate disodium also inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate disodium can be used for the research of HIV infection and gallbladder disease .
Cat. No.: HY-P1421
CAS No.: 1081110-72-6
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Cat. No.: HY-RS05711
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GPR39 Human Pre-designed siRNA Set A contains three designed siRNAs for GPR39 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17549
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Gpr39 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr39 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24008
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Gpr39 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpr39 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1306
CAS No.: 869705-22-6
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Cat. No.: HY-P1306A
CAS No.: 1312186-27-8
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Cat. No.: HY-182367
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TMN-OMe is a blood-brain barrier-permeable GPR39 agonist and a radiotracer for positron emission tomography (PET). TMN-OMe activates GPR39 by recruiting β-arrestin, exhibits highly selective binding ability in the mouse brain, and enables quantitative analysis of GPR39 at the in vivo level. TMN-OMe shows specific uptake in GPR39 knockout mice, Alzheimer's disease model (APP/PS1) mice, and blocking experiments. TMN-OMe facilitates in-depth exploration of changes in GPR39-related mechanisms in neurological diseases and is widely used in Alzheimer's disease research .
Cat. No.: HY-103007R
CAS No.: 1621175-65-2
Synonyms: GPR39-C3 (Standard)
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TC-G-1008 (Standard) is the analytical standard of TC-G-1008 (HY-103007). This product is intended for research and analytical applications. TC-G-1008 (GPR39-C3) is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively.
Cat. No.: HY-108699R
CAS No.: 1144477-35-9
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TM-N1324 (Standard) is the analytical standard of TM-N1324 (HY-108699). This product is intended for research and analytical applications. TM-N1324 is an agonist of G-Protein-Coupled Receptor 39 (GPR39) with EC50s of 9 nM/5 nM in the presence of Zn2+, and 280 nM/180 nM in the absence of Zn2+ for human/murine GPR39.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
