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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Gambogic Acid
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Gambogic Acid" in MCE Product Catalog:
6
Category:
Natural Products Guttiferae Extract Plants Garcinia hanburyi Hook. f. Disease Research Fields Cancer
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2
2 Cited Publications
Cat. No.: HY-N5024
CAS No.: 173932-75-7
Category:
Ketones, Aldehydes, Acids Guttiferae Extract Phenols Polyphenols Plants Garcinia hanburyi Hook. f. Disease Research Fields Cancer
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Gambogic amide is a potent and selective agonist of TrkA and also induces its tyrosine phosphorylation and activation of downstream signaling, including Akt and MAPK. Gambogic amide specifically interacts with the cytoplasmic juxtamembrane domain of the TrkA receptor and triggers its dimerization, leading to activation. Gambogic amide has neuroprotective activity preventing glutamate-induced neuronal cell death. Gambogic amide has improved efficacy in a transient middle cerebral artery occlusion model of stroke and could be used to study neurodegenerative diseases and stroke .
Cat. No.: HY-N10678
CAS No.: 881027-35-6
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Cat. No.: HY-N4304
CAS No.: 173867-04-4
Category:
Quinones Monophenols Anthraquinones Phenols Plants Other Families Extract Disease Research Fields Cancer
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Cat. No.: HY-N10677
CAS No.: 881027-36-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
