Gambogic Acid (Standard)
Gambogic Acid (Standard) is the analytical standard of Gambogic Acid. This product is intended for research and analytical applications. Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98%
- CAS. Nr.: 2752-65-0
- Formel: C38H44O8
- Molecular Weight:628.75
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Reinheit & Dokumentation
-
Help & FAQs
-
HY-N0087
Gambogic AcidBcl-2 Family Inhibitor -
HY-10087
NavitoclaxBcl-2 Inhibitor -
HY-50907
ABT-737Bcl-2 Family Inhibitor/BH3 Mimetic -
HY-15531
VenetoclaxBCL-2 Inhibitor -
HY-16658
Z-VAD(OMe)-FMKPan-caspase Inhibitor -
HY-13205
BelnacasanCaspase-1 Inhibitor -
HY-12466
Z-DEVD-FMKCaspase-3 Inhibitor -
HY-10396
Emricasanpan-Caspase Inhibitor -
HY-13523
PAC-1Caspase Activator -
HY-12305
Q-VD-OPhPan-caspase Inhibitor -
HY-101297
Z-IETD-FMKCaspase-8 Inhibitor -
HY-100741
S63845MCL1 Inhibitor
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS. Nr. 2752-65-0
-
Molecular Weight 628.75
-
Formel C38H44O8
-
SMILES
O=C(O)/C(C)=C\C[C@@]1(C2=O)OC(C)(C)[C@@](C[C@@]2([H])C=C34)([H])[C@]31OC5=C(C(O)=C(C=C[C@](CC/C=C(C)/C)(C)O6)C6=C5C/C=C(C)\C)C4=O
-
Synonyms
Beta-Guttiferrin (Standard)
-
Structure Classification
-
Initial Source
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Zhai D, et al. Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins. Mol Cancer Ther. 2008 Jun;7(6):1639-46. [Content Brief]
[2]. Wang LH, et al. Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling. Br J Cancer. 2014 Jan 21;110(2):341-52. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Gambogic Acid (Standard) Related Classifications
HY-N0087R Related Classifications
Powered by Bioz