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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

HEK 293 cell line

" in MedChemExpress (MCE) Product Catalog:

By Targets:	BMI1 (2) 17β-HSD (1) Apoptosis (5) Autophagy (7) CaSR (1) Endogenous Metabolite (5) Isotope-Labeled Compounds (3) Microtubule/Tubulin (5) Reactive Oxygen Species (ROS) (5) Reference Standards (1)
By Research Areas:	Cancer (7) Endocrinology (1) Neurological Disease (1)

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Isotope-Labeled Compounds

Targets Recommended: GDNF Receptor Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 BCL6 Tim3 VISTA BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12033

2-Methoxyestradiol 30+ Cited Publications 2-ME2; NSC-659853	Microtubule/Tubulin Reactive Oxygen Species (ROS) Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-15888

PTC-209 15+ Cited Publications	BMI1 Autophagy	Cancer
PTC-209 is a specific BMI-1 inhibitor with an IC₅₀ of 0.5 μM in HEK293T cell line. PTC-209 irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 shows potent anti-myeloma activity and impairs the tumor microenvironment .

HY-12033S2

2-Methoxyestradiol-d5 2-ME2-d₅; NSC-659853-d₅	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species (ROS) Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol-d₅ is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-15888A

PTC-209 hydrobromide 15+ Cited Publications	BMI1 Autophagy	Cancer
PTC-209 hydrobromide is a specific BMI-1 inhibitor with an IC₅₀ of 0.5 μM in HEK293T cell line. PTC-209 hydrobromide irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 hydrobromide shows potent anti-myeloma activity and impairs the tumor microenvironment .

HY-179475

KP-2067	CaSR	Endocrinology
KP-2067 is a form of the CaSR agonist peptide. KP-2067 can result in dose-dependent activation of CaSR in HEK293T overexpressing hCaSR cell line, with an EC₅₀ of 18.4 μM. KP-2067 significantly reduces plasma parathyroid hormone in rat model .

HY-12033S1

2-Methoxyestradiol-13C6 2-ME2-¹³C₆; NSC-659853-¹³C₆	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species (ROS) Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-12033S

2-Methoxyestradiol-13C,d3	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species (ROS) Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol- ¹³C,d₃ is the ¹³C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-157935

17β-HSD10-IN-3	17β-HSD	Neurological Disease
17β-HSD10-IN-3 (compound 23) is a 17β-HSD10 inhibitor with the IC₅₀ of 5.59 μM. 17β-HSD10-IN-3 shows no cell cytotoxicity toward the HEK-293 cell line up to 20 μM .

HY-12033R

2-Methoxyestradiol (Standard) 2-ME2 (Standard); NSC-659853 (Standard)	Microtubule/Tubulin Reactive Oxygen Species (ROS) Apoptosis Autophagy Endogenous Metabolite Reference Standards	Cancer
2-Methoxyestradiol (Standard) is the analytical standard of 2-Methoxyestradiol. This product is intended for research and analytical applications. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

Cat. No.	Product Name	Target	Research Area

HY-179475

KP-2067	CaSR	Endocrinology
KP-2067 is a form of the CaSR agonist peptide. KP-2067 can result in dose-dependent activation of CaSR in HEK293T overexpressing hCaSR cell line, with an EC₅₀ of 18.4 μM. KP-2067 significantly reduces plasma parathyroid hormone in rat model .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-12033

2-Methoxyestradiol 30+ Cited Publications 2-ME2; NSC-659853	Monophenols Classification of Application Fields Disease markers Phenols Endocrine diseases Endogenous metabolite Disease Research Fields Steroids Cancer Source Classification	Microtubule/Tubulin Reactive Oxygen Species (ROS) Apoptosis Autophagy Endogenous Metabolite
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-12033R

2-Methoxyestradiol (Standard) 2-ME2 (Standard); NSC-659853 (Standard)	Structural Classification Monophenols Disease markers Phenols Endocrine diseases Endogenous metabolite Steroids Cancer Source Classification	Microtubule/Tubulin Reactive Oxygen Species (ROS) Apoptosis Autophagy Endogenous Metabolite Reference Standards
2-Methoxyestradiol (Standard) is the analytical standard of 2-Methoxyestradiol. This product is intended for research and analytical applications. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

Species:	Human (2) Canine (1)
Tag:	Tag Free (2) Fc (1)
Source:	HEK293 (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73074

	GDNF Protein, Human (HEK293) 1 Publications Verification Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Human	HEK293
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Human (HEK293) is produced in HEK293 cells, and consists of 103 amino acids (R83-I185).

HY-P75169

	GDNF Protein, Canine (HEK293, Fc) Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Canine	HEK293
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a N-Terminal Fc-tag. It consists of 103 amino acids (R109-I211).

HY-P704369

	GDNF Protein, Human (134a.a, HEK293) Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Human	HEK293
	GDNF Protein, Human (134a.a, HEK293) is the recombinant human-derived GDNF protein, expressed by HEK293, with tag free tag.

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Cat. No.	Product Name	Chemical Structure

HY-12033S2

2-Methoxyestradiol-d5
2-Methoxyestradiol-d₅ is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

2-Methoxyestradiol-d5

2-Methoxyestradiol-d₅ is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-12033S1

2-Methoxyestradiol-13C6
2-Methoxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

2-Methoxyestradiol-13C6

2-Methoxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-12033S

2-Methoxyestradiol-13C,d3
2-Methoxyestradiol- ¹³C,d₃ is the ¹³C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

2-Methoxyestradiol-13C,d3

2-Methoxyestradiol- ¹³C,d₃ is the ¹³C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

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