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HIV-1 Env gp120

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HIV (4)
By Research Areas:	Infection (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Recombinant Proteins

Targets Recommended: HIV Integrase HIV HIV Protease P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0788

Indoline	HIV	Infection
Indoline is a derivative of Indole (HY-W001132). Indoline can use as the basic structure for CD4 mimetic compounds (CD4mcs), which triggers conformational changes of the *HIV-1* envelope glycoprotein (Env) in advance, and causes viral inactivation. Indoline binds to gp120. Indoline CD4mcs can inhibit *HIV-1_AD8* with an IC₅₀ in the micromolar range .

HY-125183

BMS-818251	HIV	Infection
BMS-818251 is a *HIV-1* attachment and entry inhibitor. BMS-818251 binds to **HIV-1 Env gp120, interferes with viral attachment and entry processes, and inhibits HIV-1 viral replication. BMS-818251 can be used in studies related to HIV-1** infection .

HY-139989

NBD-14270	HIV	Infection
NBD-14270, a pyridine analogue, is a potent *HIV-1* entry antagonist with an IC₅₀ of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC₅₀>100 μM) .

HY-182376

JRC-I-191	HIV	Infection
JRC-I-191 is an anti-HIV-1 agent. JRC-I-191 inhibits HIV-1 YU-2 entry into cells. JRC-I-191 does not inhibit infection of cells by amphotropic murine leukemia virus. JRC-I-191 can be used for the research of HIV-1 infection .

Indoline	Biochemical Assay Reagents
Indoline is a derivative of Indole (HY-W001132). Indoline can use as the basic structure for CD4 mimetic compounds (CD4mcs), which triggers conformational changes of the *HIV-1* envelope glycoprotein (Env) in advance, and causes viral inactivation. Indoline binds to gp120. Indoline CD4mcs can inhibit *HIV-1_AD8* with an IC₅₀ in the micromolar range .

Species:	Virus (4)
Tag:	His (4)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P74118

	*envelope glycoprotein gp120* Protein, HIV-1 (ACY40659, HEK293, His)** Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (ACY40659, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74119

	*envelope glycoprotein gp120* Protein, HIV-1 (AFM77980, HEK293, His)** Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (AFM77980, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74120

	*envelope glycoprotein gp120* Protein, HIV-1 (AAC57427, HEK293 , His)** Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (AAC57427, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74121

	*envelope glycoprotein gp120* Protein, HIV-1 (AAA44191, HEK293 , His)** Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (AAA44191, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-10*His labeled tag.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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