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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
HVA
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "HVA" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: (+)-DTBZ; (+)-α-Dihydrotetrabenazine; (+)-α-DHTBZ
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NBI-98782 is a high affinity and selectivity vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki of 3 nM. NBI-98782 has antipsychotic activity .
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Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor.
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MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist (EC50=50 nM) with greater than 50-fold selectivity for δ, μ, and κ opioid receptors. MRGPRX1 agonist 1 is inactive against MRGPRC11. MRGPRC11 inhibits high voltage-activated (HVA) Ca 2+ currents, reduces neurotransmitter release, and mitigates nociceptive transmission in the spinal cord. MRGPRX1 agonist 1 is useful for the study of chronic pain, especially neuropathic pain .
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Ro 41-0960 is a CNS-penetrant, orally active catechol-O-methyl transferase (COMT) inhibitor. Ro 41-0960 reduces dopamine catabolism, increases striatal dopamine and DOPAC levels, decreases striatal HVA levels, induces apoptosis, inhibits proliferation and extracellular matrix formation in uterine fibroid cells. Ro 41-0960 arrests or shrinks uterine fibroid lesions in rats. Ro 41-0960 can be used for the research of Parkinson’s disease, uterine leiomyomas, and breast cancer .
Cat. No.: HY-W002110
CAS No.: 1131-94-8
Synonyms: 3-Hydroxy-4-methoxyphenylacetic acid; iso-HVA; Homoisovanillic acid
Category:
Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Cancer
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Cat. No.: HY-42849
CAS No.: 53583-79-2
Synonyms: LIN-1418
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Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor.
Cat. No.: HY-P4029
CAS No.: 161012-10-8
Cat. No.: HY-19061
CAS No.: 111757-17-6
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CGP 28014 is a catechol-O-methyltransferase inhibitor. CGP 28014 can lower HVA levels and increase DOPAC levels in the striatum of rats, making it useful for research on Parkinson's disease .
Cat. No.: HY-W002110R
CAS No.: 1131-94-8
Synonyms: 3-Hydroxy-4-methoxyphenylacetic acid (Standard); iso-HVA (Standard); Homoisovanillic acid (Standard)
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Cat. No.: HY-42849AR
CAS No.: 23694-17-9
Synonyms: LIN-1418 hydrochloride (Standard)
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Sultopride hydrochloride (Standard) is the analytical standard of Sultopride hydrochloride. This product is intended for research and analytical applications. Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
