11 Results for "

Human carboxylesterase 2

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "Human carboxylesterase 2" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0235
CAS No.: 10309-37-2
Synonyms: (S)-(+)-Bakuchiol
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
loading...
    loading...
Cat. No.: HY-N3474
CAS No.: 94805-83-1
Isolicoflavonol potently inhibits hCES2A (Human carboxylesterase 2)-mediated fluorescein diacetate hydrolysis in a reversible and mixed inhibition manner, with Ki values less than 1.0 μM .
loading...
    loading...
Cat. No.: HY-N0855
CAS No.: 155521-46-3
Synonyms: Alisol-G; 25-Anhydroalisol A
Alisol G (25-Anhydroalisol A) is a human carboxylesterase 2 (hCES2) inhibitor with an IC50 of 3.85 μM. Alisol G exhibits cytotoxic activity against human cancer cells, antibacterial activity against Gram-positive strains, and anti-hepatitis B virus activity. Alisol G can be used in research related to lung cancer, breast cancer, prostate cancer, bacterial infections, and HBV infections .
loading...
    loading...
Cat. No.: HY-N3921
CAS No.: 126716-36-7
Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis .
loading...
    loading...
Cat. No.: HY-N3413
CAS No.: 254886-77-6
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively .
loading...
    loading...
Cat. No.: HY-N0235R
CAS No.: 10309-37-2
Synonyms: (S)-(+)-Bakuchiol (Standard)
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
loading...
    loading...
Cat. No.: HY-P76192A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES2; carboxylesterase 2 (Intestine, Liver); carboxylesterase 2; Cocaine Esterase; CE-2; Intestinal carboxylesterase; Liver carboxylesterase-2; ICE; Carboxylic Ester Hydrolase; CES2A1; PCE-2; Methylumbelliferyl-Acetate Deacetylase 2; HCE-2
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P76192
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES2; carboxylesterase 2 (Intestine, Liver); carboxylesterase 2; Cocaine Esterase; CE-2; Intestinal carboxylesterase; Liver carboxylesterase-2; ICE; Carboxylic Ester Hydrolase; CES2A1; PCE-2; Methylumbelliferyl-Acetate Deacetylase 2; HCE-2
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-176465
CAS No.: 3037959-47-7
Research Areas:  

Inflammation/Immunology

CES2A-IN-3 (Compound 9d) is a potent serine-targeting covalent human carboxylesterase 2A (hCES2A) inhibitor with an IC50 value of 0.12 nM. CES2A-IN-3 is promising for research of diarrhea and ulcerative colitis .
loading...
    loading...
Cat. No.: HY-155228
Research Areas:  

Inflammation/Immunology

hCES2A-IN-2 (Compound 44) is an orally active human carboxylesterase 2 (hCES2A) inhibitor (IC50: 5.02 μM). hCES2A-IN-2 improves Irinotecan (HY-16562)-induced delayed diarrhea .
loading...
    loading...
Cat. No.: HY-147915
CAS No.: 2416220-53-4
Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids .
loading...
    loading...
  • 1