35 Results for "

Immunosuppressant1

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "Immunosuppressant1" in MCE Product Catalog:

Cat. No.: HY-156520
CAS No.: 1224571-03-2
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Immunosuppressant-1 (Compound 31) inhibits anti-CD3/anti-CD28 co-stimulated T-cell proliferation. Immunosuppressant-1 has immunosuppressive activity, and induces apoptosis by activating caspase-3 and PARP in activated lymph node cells [1].
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1470
1470 Publications Verification
Cat. No.: HY-10219
CAS No.: 53123-88-9
Purity:  99.94%
Synonyms: Sirolimus; AY-22989; NSC 226080
Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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80
80 Cited Publications
Cat. No.: HY-12005
CAS No.: 162359-56-0
Purity:  99.95%
Synonyms: FTY720
Target:  

LPL Receptor PAK

Research Areas:  

Inflammation/Immunology Cancer

Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant .
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80
80 Cited Publications
Cat. No.: HY-11063
CAS No.: 162359-55-9
Purity:  99.97%
Synonyms: FTY720 free base
Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant .
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5
5 Cited Publications
Cat. No.: HY-17470
CAS No.: 50924-49-7
Synonyms: NSC 289637; HE 69
Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC50 of approximately 100 μM for anti-HCV activity. Immunosuppressant . Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively .
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1
1 Cited Publications
Cat. No.: HY-135005
CAS No.: 856699-18-8
Purity:  99.3%
Biliverdin hydrochloride, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin hydrochloride is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin hydrochloride is anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant .
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1
1 Cited Publications
Cat. No.: HY-10219S
CAS No.: 392711-19-2
Purity:  ≥93.0%
Synonyms: Sirolimus-d3; AY-22989-d3; NSC 226080-d3
Rapamycin-d3 (Sirolimus-d3; AY-22989-d3; NSC 226080-d3) is the deuterated-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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1
1 Cited Publications
Cat. No.: HY-10219G
CAS No.: 53123-88-9
Synonyms: Sirolimus (GMP); AY-22989 (GMP); NSC 226080 (GMP)
Rapamycin (Sirolimus) (GMP) is Rapamycin (HY-10219) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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Cat. No.: HY-13609
CAS No.: 14484-47-0
Purity:  98.98%
Deflazacort, a glucocorticoid, is an inactive proagent and is converted rapidly to the active metabolite 21-desacetyldeflazacort. Deflazacort is used as an anti-inflammatory and immunosuppressant .
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Cat. No.: HY-10219R
CAS No.: 53123-88-9
Synonyms: Sirolimus (Standard); AY-22989 (Standard); NSC 226080 (Standard)
Rapamycin (Standard) (Sirolimus (Standard)) is the analytical standard of Rapamycin (HY-10219). This product is intended for research and analytical applications. Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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Cat. No.: HY-10219GL
CAS No.: 53123-88-9
Purity:  98.8%
Synonyms: Sirolimus (GMP Like); AY-22989 (GMP Like); NSC 226080 (GMP Like)
Rapamycin (Sirolimus) GMP Like is Rapamycin (HY-10219) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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Cat. No.: HY-10219S1
Purity:  97.05%
Synonyms: Sirolimus-13C,d3; AY-22989-13C,d3 NSC 226080-13C,d3
Rapamycin- 13C,d3 (Sirolimus- 13C,d3) is the 13C, deuterated-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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Cat. No.: HY-17420S
CAS No.: 173547-45-0
Cyclophosphamide-d4 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant .
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Cat. No.: HY-W012595A
CAS No.: 1896-62-4
Synonyms: trans-Benzalacetone
trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant .
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Cat. No.: HY-11063R
CAS No.: 162359-55-9
Synonyms: FTY720 free base (Standard)
Fingolimod (Standard) is the analytical standard of Fingolimod. This product is intended for research and analytical applications. Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant .
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Cat. No.: HY-17470R
CAS No.: 50924-49-7
Synonyms: NSC 289637 (Standard); HE 69 (Standard)
Mizoribine (Standard) is the analytical standard of Mizoribine. This product is intended for research and analytical applications. Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC50 of approximately 100 μM for anti-HCV activity. Immunosuppressant . Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively .
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Cat. No.: HY-W424539
CAS No.: 1715-33-9
Research Areas:  

Inflammation/Immunology

Prednisolone (sodium succinate) is an anti-inflammatory corticosteroid and a prodrug of the glucocorticoid prednisolone. Prednisolone (sodium succinate) is used as an immunosuppressant .
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Cat. No.: HY-11063S
CAS No.: 1346747-38-3
Purity:  99.11%
Synonyms: FTY720 free based-d4
Fingolimod-d4 is the deuterium labeled Fingolimod. Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant .
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Cat. No.: HY-W012595AR
CAS No.: 1896-62-4
Synonyms: trans-Benzalacetone (Standard)
trans-Benzylideneacetone (Standard) is the analytical standard of trans-Benzylideneacetone. This product is intended for research and analytical applications. trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant[1].
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Cat. No.: HY-13609S
Deflazacort-d5 is the deuterium labeled Deflazacort. Deflazacort, a glucocorticoid, is an inactive proagent and is converted rapidly to the active metabolite 21-desacetyldeflazacort. Deflazacort is used as an anti-inflammatory and immunosuppressant .
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