2. Metabolic Enzyme/Protease
  3. Phospholipase
  4. trans-Benzylideneacetone

trans-Benzylideneacetone  (Synonyms: trans-Benzalacetone)

Cat. No.: HY-W012595A Purity: 99.29%
COA Handling Instructions

trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant.

For research use only. We do not sell to patients.

trans-Benzylideneacetone Chemical Structure

trans-Benzylideneacetone Chemical Structure

CAS No. : 1896-62-4

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Based on 1 publication(s) in Google Scholar

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Description

trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant[1].

IC50 & Target[1]

PLA2

 

In Vitro

Benzylideneacetone (trans-Benzylideneacetone; 0.005, 0.05, 0.5, 5, 50, 500, 5000 μM) inhibits hemocytespreading behavior of hemocytes of S. exigua larvae. Benzylideneacetone enhances virulence of Bacillus thuringiensisagainst beet armyworm[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

146.19

Appearance

<39°C Solid,>42°C Liquid

Formula

C10H10O
CAS No.
SMILES

CC(/C=C/C1=CC=CC=C1)=O.[E]
Structure Classification
Source

a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (684.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8404 mL 34.2021 mL 68.4041 mL
5 mM 1.3681 mL 6.8404 mL 13.6808 mL
10 mM 0.6840 mL 3.4202 mL 6.8404 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (17.10 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (17.10 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (17.10 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.29%

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

trans-Benzylideneacetone1896-62-4trans-BenzalacetonePhospholipasegram-negativeentomopathogenicbacteriumXenorhabdusnematophilaimmunosuppressantInhibitorinhibitorinhibit

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