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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Ins(l,4,5)P3
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Ins(l,4,5)P3" in MCE Product Catalog:
2
2 Cited Publications
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GNF362 is a selective, potent, and orally bioavailable inhibitor of inositol trisphosphate 3’ kinase B (Itpkb) with an IC50 of 9 nM. GNF362 also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively. Inositol trisphosphate 3’ kinase B (Itpkb) is a Ca 2+-dependent kinase, which phosphorylates the 3’ position of Ins (1,4,5) P3 to generate inositol 1,3,4,5-tetrakisphosphate [Ins (1,3,4,5) P4] .
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1 Cited Publications
Cat. No.: HY-W795960
CAS No.: 108340-81-4
Cat. No.: HY-133690
CAS No.: 210488-61-2
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D-myo-Inositol-1,3,4,5-tetraphosphate sodium is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase.
Cat. No.: HY-173537
CAS No.: 154278-46-3
Synonyms: Ins(1,2,4,5)P4 tetrasodium salt; 1,2,4,5-IP4 tetrasodium salt
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D-myo-Inositol-1,2,4,5-tetraphosphate (DL-Ins-(1,2,4,5)P4) tetrasodium is raracemic regioisomer of myo-inositol tetrakisphosphates (IP4s). D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium is an Ins(1,4,5)P3 receptor agonist with a Ki of 11 nM. D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium induces Ca 2+ mobilization with an EC50 value of 0.22 μM in CHO cells .
Cat. No.: HY-W127317
CAS No.: 102850-29-3
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EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P2 phosphatase and Ins(1,4,5)P3 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity .
Cat. No.: HY-175070
Synonyms: Ins(2,4,5)P3 sodium salt; 2,4,5-IP3 sodium salt
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D-myo-Inositol-2,4,5-triphosphate (Ins(2,4,5)P3) (sodium salt) is a second messenger produced in cells by phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. D-myo-Inositol-2,4,5-triphosphate (sodium salt) can open calcium channels and increase intracellular calcium upon binding to its receptors on the endoplasmic reticulum. D-myo-Inositol-2,4,5-triphosphate (sodium salt) also acts as a partial agonist at rat hepatic IP3 receptors. D-myo-Inositol-2,4,5-triphosphate (sodium salt) can be studied in research on calcium ions signaling pathway .
Cat. No.: HY-W788040
CAS No.: 1246355-68-9
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Inositol 1,3,4,5-tetraphosphate tetraammonium is an inositol tetraphosphate. Inositol 1,3,4,5-tetraphosphate tetraammonium is metabolically produced from Ins (1,4,5) P3 via 3-kinase, participates in intracellular signal transduction systems, and elevates intracellular calcium concentrations when present .
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Protocols
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