5 Results for "

KPT330

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "KPT330" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-17536
CAS No.: 1393477-72-9
Synonyms: KPT-330
Target:  

CRM1 PANoptosis

Research Areas:  

Infection Cancer

Selinexor (KPT-330) is an analog of KPT-185 (HY-15611). Selinexor is an orally active, selective CRM1 inhibitor that inhibits tumor growth by inducing PANoptosis .
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Cat. No.: HY-17536R
CAS No.: 1393477-72-9
Synonyms: KPT-330 (Standard)
Research Areas:  

Cancer

Selinexor (Standard) is the analytical standard of Selinexor. This product is intended for research and analytical applications. Selinexor (KPT-330) is an analog of KPT-185 (HY-15611). Selinexor is an orally active, selective CRM1 inhibitor that inhibits tumor growth by inducing PANoptosis .
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Cat. No.: HY-17536S
Synonyms: KPT-330-d5
Selinexor-d5 (KPT-330-d5) isthe deuterium labeled Selinexor (HY-17536). Selinexor (KPT-330), an analog of KPT-185, is an orally active and selective CRM1 inhibitor .
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Cat. No.: HY-W338346
CAS No.: 2016-36-6
Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer .
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Cat. No.: HY-17536A
CAS No.: 1421923-86-5
Synonyms: (E)-KPT-330
Target:  

CRM1

Research Areas:  

Cancer

(E)-Selinexor ((E)-KPT-330) is the E-isomer of Selinexor (HY-17536). Selinexor is the selective, orally active CRM1 inhibitor .
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