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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
LPAR1
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "LPAR1" in MCE Product Catalog:
Cat. No.: HY-162267
CAS No.: 3032275-33-2
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LPAR1 antagonist 1 (compound 18) is a potent, oral active and selective LPAR1 antagonist with the IC50 of 3.3 nM. LPAR1 antagonist 1 can be used for study of fibrosis [1].
Cat. No.: HY-159983
CAS No.: 2750508-72-4
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GS-2278 is an LPAR1 (lysophosphatidic acid receptor 1) antagonist with potential for research in idiopathic pulmonary fibrosis (IPF) [1].
Cat. No.: HY-160661
CAS No.: 1664336-46-2
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LPAR1 antagonist 2 (example 76) is an LPAR1 antagonist with an average IC50 of 130 nM [1].
Cat. No.: HY-RS07746
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LPAR1 Human Pre-designed siRNA Set A contains three designed siRNAs for LPAR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07747
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Lpar1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lpar1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07748
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Lpar1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lpar1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-171806
CAS No.: 1257213-96-9
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BMT-136088 is a LPAR1 antagonist [1]. 11C-BMT-136088 can be used as a positron emission tomography (PET) radioligand to quantify specific binding to LPA1 in lung.
Cat. No.: HY-149018
CAS No.: 2969213-59-8
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ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) with IC50 of 218 nM but lost its inhibitory activity of LPAR1 [1].
Cat. No.: HY-120282
CAS No.: 1802079-45-3
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ONO-9910539 is a lysophosphatidic acid receptor 1 (LPAR1) antagonist. ONO-9910539 is applicable to the research of idiopathic pulmonary fibrosis [1].
Cat. No.: HY-181931
CAS No.: 3058084-21-9
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Autotaxin-IN-8 (Compound 14E) is an orally active Autotaxin inhibitor with an IC50 of 14.2 nM against hAutotaxin. Autotaxin-IN-8 inhibits Autotaxin activity, MAPK activation, LPAR1 and p-ERK1/2. Autotaxin-IN-8 reduces the phosphorylation levels of JNK and p38. Autotaxin-IN-8 decreases collagen deposition in a mouse model of pulmonary fibrosis. Autotaxin-IN-8 can be used in research related to pulmonary fibrosis [1].
Cat. No.: HY-182787
CAS No.: 3057457-78-7
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LPA1 receptor antagonist-7 is a LPA1 antagonist. LPA1 receptor antagonist-7 blocks downstream signaling pathways mediated by LPA1. LPA1 receptor antagonist-7 inhibits LPA-induced migration and invasion of cancer cells. LPA1 receptor antagonist-7 can be used for the research of triple-negative breast cancer [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
