ATX inhibitor 22
ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) with IC50 of 218 nM but lost its inhibitory activity of LPAR1.
For research use only. We do not sell to patients.
- CAS No.: 2969213-59-8
- Formula: C19H17Cl3F2N2O4S
- Molecular Weight:513.77
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
|
Autotaxin 218 nM (IC50) |
Chemical Information
-
CAS No. 2969213-59-8
-
Molecular Weight 513.77
-
Formula C19H17Cl3F2N2O4S
-
SMILES
CS(=O)(N(C1CCOCC1)C2=C(C=C(C(C(NC3=CC(F)=C(C(F)=C3)Cl)=O)=C2)Cl)Cl)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)