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Cat. No.: HY-120282

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ONO-9910539

ONO-9910539 is a lysophosphatidic acid receptor 1 (LPAR1) antagonist. ONO-9910539 is applicable to the research of idiopathic pulmonary fibrosis.

For research use only. We do not sell to patients.

CAS No.: 1802079-45-3
Formula: C₃₂H₃₇NO₈
Molecular Weight:563.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ONO-9910539 Chemical Structure

CAS No.: 1802079-45-3

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Biological Activity
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Chemical Information
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Biological Activity

Description

ONO-9910539 is a lysophosphatidic acid receptor 1 (LPAR1) antagonist. ONO-9910539 is applicable to the research of idiopathic pulmonary fibrosis^[1].

All LPL Receptor Isoforms :

In Vitro

ONO-9910539 forms hydrogen bonding interactions between its methyl ketone carbonyl group and Trp210, and between its chiral secondary hydroxyl group and Gln125^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1802079-45-3
Molecular Weight 563.65
Formula C₃₂H₃₇NO₈
SMILES

[C@@H]([C@H](CN1C=C(C(OC)=O)C(CCC(O)=O)=C1)CC2CC=3C(C2)=CC=CC3)(O)C4=CC(OC)=C(C(C)=O)C(OC)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nguyen LP, et al. Discovery of Chemical Scaffolds as Lysophosphatidic Acid Receptor 1 Antagonists: Virtual Screening, In Vitro Validation, and Molecular Dynamics Analysis. ACS Omega. 2023;8(43):40375-40386. Published 2023 Oct 18. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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ONO-9910539

All LPL Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ONO-9910539 Related Classifications

HY-120282 Related Classifications