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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
119 Results for "
Low-density lipoprotein receptor
" in MedChemExpress (MCE) Product Catalog:
Products (119)
119 Results for "Low-density lipoprotein receptor" in MCE Product Catalog:
50
50 Publications Verification
Research Areas:
T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXRα . T0901317 activates FXR with an EC50 of 5 μM . T0901317 is RORα and RORγ dual inverse agonist with Ki values of 132 nM and 51 nM, respectively . T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice .
14
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
14
14 Cited Publications
Cat. No.: HY-B0144
CAS No.: 147526-32-7
Synonyms: NK-104 hemicalcium; Pitavastatin hemicalcium
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
5
5 Cited Publications
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
5
Target:
5
5 Cited Publications
Target:
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P70235
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LDLR; LDL receptor; Low density lipoprotein receptor; Low-density lipoprotein receptor Class A Domain-Containing Protein 3; Low-density lipoprotein receptor; Familial Hypercholesterolemia; LDLCQ2; Low density lipoprotein
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P76479A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRPAP1; Low density lipoprotein-Related Protein-Associated Protein 1 (Alpha-2-Macroglobulin receptor-Associated Protein 1); Prev. A2MRAP; Low density lipoprotein receptor-Related Protein-Associated Protein 1; Prev. RAP; 39 KDa receptor-Associated Protein
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P76479
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRPAP1; Low density lipoprotein-Related Protein-Associated Protein 1 (Alpha-2-Macroglobulin receptor-Associated Protein 1); Prev. A2MRAP; Low density lipoprotein receptor-Related Protein-Associated Protein 1; Prev. RAP; 39 KDa receptor-Associated Protein
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P7151
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL16; CXCLG16; C-X-C Motif Chemokine Ligand 16; Scavenger receptor For Phosphatidylserine And Oxidized Low density lipoprotein; SR-PSOX; Chemokine (C-X-C Motif) Ligand 16; SRPSOX; Small-Inducible Cytokine B16; Transmembrane Chemokine CXCL16; CXC Chemokine Ligand 16; C-X-C Motif Chemokine 16; SCYB16
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-W510159
CAS No.: 56005-10-8
Target:
1
1 Cited Publications
Cat. No.: HY-N2339
CAS No.: 61510-09-6
Synonyms: Cholesteryl docosanoate; Cholesterol behenate
Target:
1
1 Cited Publications
Cat. No.: HY-P76478A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRPAP1; Low density lipoprotein-Related Protein-Associated Protein 1 (Alpha-2-Macroglobulin receptor-Associated Protein 1); Prev. A2MRAP; Low density lipoprotein receptor-Related Protein-Associated Protein 1; Prev. RAP; 39 KDa receptor-Associated Protein
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72961
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL16; CXCLG16; C-X-C Motif Chemokine Ligand 16; Scavenger receptor For Phosphatidylserine And Oxidized Low density lipoprotein; SR-PSOX; Chemokine (C-X-C Motif) Ligand 16; SRPSOX; Small-Inducible Cytokine B16; Transmembrane Chemokine CXCL16; CXC Chemoki
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-114164G
CAS No.: 9002-04-4
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Murine Thrombin is a murine serine protease that plays a central role in blood coagulation. Murine Thrombin stimulates macrophages to polarize into a unique phenotype characterized by anti-inflammatory and pro-repair properties. Murine Thrombin activates PAR1, induces the production of MCP-1, MMP3 and VEGF in mouse intervertebral discs, and causes degradation of the cartilage matrix and destruction of intervertebral disc structure. Murine Thrombin activity increases significantly in paraoxon-induced status epilepticus .
Synonyms: KB2115
Target:
Research Areas:
Eprotirome (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist. KB2115 has modestly higher affinity for TRβ than for TRα. Eprotirome reduces low-density lipoprotein (LDL) cholesterol concentrations. Eprotirome can be used for dyslipidemias and obesity research .
Cat. No.: HY-P10502
CAS No.: 2378836-93-0
Cat. No.: HY-B0374
CAS No.: 75438-57-2
Synonyms: BDF5895
Research Areas:
Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I1-R) agonist. Moxonidine activates imidazoline I1 receptors and α2 adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis .
Cat. No.: HY-B0374A
CAS No.: 75536-04-8
Synonyms: BDF5895 hydrochloride
Research Areas:
Moxonidine (BDF5895) hydrochloride is an orally active imidazoline type 1 receptor (I1-R) agonist. Moxonidine hydrochloride activates imidazoline I1 receptors and α2 adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine hydrochloride reduces atherosclerotic lesions and lowers blood pressure. Moxonidine hydrochloride can be used in the study of hypertension, heart failure, and atherosclerosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
