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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
MCUB
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "MCUB" in MCE Product Catalog:
Cat. No.: HY-RS08253
Target:
Domaines de recherche:
MCUB Human Pre-designed siRNA Set A contains three designed siRNAs for MCUB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20771
Target:
Domaines de recherche:
Mcub Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mcub gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17019
Target:
Domaines de recherche:
Areg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Areg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27285
Target:
Domaines de recherche:
Mcub Rat Pre-designed siRNA Set A contains three designed siRNAs for Mcub gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-191348
CAS No.: 1424565-75-2
Domaines de recherche:
TF-PPAO is a blood-brain barrier-penetrant mitochondrial calcium uptake inducer (human Kd = 2.82 μM). TF-PPAO binds the MCUB transmembrane pocket and disrupts MCUB-MCU binding, thereby relieving MCUB-mediated restriction, activating pyruvate dehydrogenase activity, and inducing mitochondrial reactive oxygen species (ROS) and oxidative DNA damage. TF-PPAO acts as a radiosensitizer, inhibits tumor growth, and exhibits intracranial tumor accumulation ability, with no detectable systemic toxicity. TF-PPAO can be used for research on glioblastoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
