Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
MID
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "MID" in MCE Product Catalog:
7
7 Cited Publications
Target:
Research Areas:
LM11A-31 dihydrochloride, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .
7
7 Cited Publications
Target:
Research Areas:
LM11A-31, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .
Cat. No.: HY-P99317
CAS No.: 955085-14-0
Synonyms: LY-2062430
Target:
Research Areas:
Solanezumab (LY-2062430) is a humanized monoclonal IgG1 antibody directed against the mid-domain of the amyloid-β (Aβ) peptide. Solanezumab binds to the mid-domain of monomeric amyloid-beta to slow brain amyloid accumulation. Solanezumab can be used for the research of Alzheimer’s disease .
Cat. No.: HY-W854844A
CAS No.: 3065021-33-9
Research Areas:
JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders .
Target:
Research Areas:
MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake .
Cat. No.: HY-176975
CAS No.: 3056559-92-0
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
DRP1 Allosteric-IN-3 (Compound 2b) is an allosteric inhibitor of DRP1. Its IC50 value for the DRP1:MiD49 protein-protein interaction is 11 μM. DRP1 Allosteric-IN-3 can be used to study various diseases related to mitochondrial division disorders .
Cat. No.: HY-P5444
CAS No.: 149924-99-2
Cat. No.: HY-W710399
CAS No.: 17708-08-6
Synonyms: DG(16:0/0:0/18:0); 1-Palmitin-3-Stearin
Target:
Research Areas:
1-Palmitoyl-3-stearoyl-rac-glycerol is a diacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 position and stearic acid (HY-B2219) at the sn-3 position. It has been found in palm-based diacylglycerols produced from palm stearin, palm mid fraction, palm oil, and palm olein, as well as in wheat bran and brewer’s spent grain extracts.
Cat. No.: HY-RS08434
Target:
Research Areas:
MID1 Human Pre-designed siRNA Set A contains three designed siRNAs for MID1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08436
Target:
Research Areas:
MID2 Human Pre-designed siRNA Set A contains three designed siRNAs for MID2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08435
Target:
Research Areas:
MID1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MID1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19281
Target:
Research Areas:
Mid1ip1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mid1ip1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25771
Target:
Research Areas:
Mid1ip1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mid1ip1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N12921
CAS No.: 42513-42-8
Category:
Target:
Cat. No.: HY-RS18951
Target:
Research Areas:
Mid1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mid1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25441
Target:
Research Areas:
Mid1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mid1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176973
CAS No.: 1359386-11-0
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
DRP1 Allosteric-IN-1 (Compound 1) is an allosteric inhibitor of DRP1 with an IC50 value for the DRP1:MiD49 protein-protein interaction of 3.6 μM. DRP1 Allosteric-IN-1 can be used to study various diseases related to mitochondrial division disorders .
Cat. No.: HY-176974
CAS No.: 3056559-91-9
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
DRP1 Allosteric-IN-2 (Compound 2a) is an allosteric inhibitor of DRP1. Its IC50 value for the DRP1:MiD49 protein-protein interaction is 4.3 μM. DRP1 Allosteric-IN-2 can be used to study various diseases related to mitochondrial division disorders .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
