1 Result for "

MM121

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MM121" in MCE Product Catalog:

Cat. No.: HY-P99268
CAS No.: 1334296-12-6
Synonyms: SAR 256212; MM 121

Target:  

EGFR Apoptosis

Domaines de recherche:  

Cancer

Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models .
loading...
    loading...