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Methyl Blue

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By Targets:	Bacterial (2) Biochemical Assay Reagents (1) EGFR (1) Endogenous Metabolite (1) Environmental Pollutants (1) Fluorescent Dye (2) PROTACs (1) Reference Standards (1)
By Research Areas:	Cancer (1) Infection (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0003

**Methyl Blue**	Environmental Pollutants Bacterial	Infection
Methyl blue belongs to the group of triaminotriphenylmethane dyes. Methyl blue is widely used as antiseptic dye in polychrome staining method and has applications in histological and microbiological staining solutions. Methyl blue has been used as a model to study the effect of various catalysts on photodegradation of dyes .

HY-D1416

HMBR 1 Publications Verification	Fluorescent Dye	Others
HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability .

HY-15932

TOOS TOOS sodium salt	Biochemical Assay Reagents	Others
TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .

HY-D0026

AMCA,SE 7-Amino-4-Methyl-3-coumarinacetic acid N-succinimidyl ester	Fluorescent Dye	Others
AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a bright blue fluorescent dye. AMCA,SE reacts with amino groups and is excited by ultraviolet light. AMCA,SE can be used for amine reactive labeling (Ex/Em = 354/440 nm) .

HY-157579

MS154N	PROTACs EGFR	Cancer
MS154N (compound 28) is the negative control of MS39 (HY-157581). MS154N is composed of PROTAC target protein ligand EGFR ligand-11 (HY-168305) (red part), E3 ligase ligand 4-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (HY-W441376) (blue part) and PROTAC Linker 8-Iodooctan-1-amine (HY-168306) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is Me-Thalidomide-O-C8-NH2 (HY-168307) .

HY-W714137

(6-Isothiocyanatohexyl)(methyl)sulfane Lesquerellin; 6-Methylthiohexyl isothiocyanate	Bacterial	Infection
(6-Isothiocyanatohexyl)(methyl)sulfane (Lesquerellin; 6-Methylthiohexyl isothiocyanate) is an isothiocyanate found in wasabi (W. japonica) and has various biological activities. (6-Isothiocyanatohexyl)(methyl)sulfane is active against the bacterium Bacillus subtilis and the fungus T. mentagrophytes (MIC=25 μg/mL). (6-Isothiocyanatohexyl)(methyl)sulfane also has anthelmintic activity against blue mussel (M. edulis). (6-Isothiocyanatohexyl)(methyl)sulfane has antifouling activity when applied to polyvinyl chloride (PVC) panels at a concentration of 50 μmol/cm2 in a conventional immersion test.

HY-N3290

Methyl p-methoxyhydrocinnamate Methyl p-methoxyphenylpropionate	Others	Others
Methyl p-methoxyhydrocinnamate is extracted from in liquid culture by the blue stain fungus Ophiostoma crassioaginata .

HY-W722087

3,6-Dimethylundecane	Endogenous Metabolite	Others
3,6-Dimethylundecane is a type of di-methyl alkanoid compound. 3,6-Dimethylundecane is one of the various branched alkanes identified in the metabolic products of the desert blue-green algae Microcoleus vaginatus .

HY-N3290R

Methyl p-methoxyhydrocinnamate (Standard) Methyl p-methoxyphenylpropionate (Standard)	Others Reference Standards	Others
Methyl p-methoxyhydrocinnamate (Standard) (Methyl p-methoxyphenylpropionate (Standard)) is the analytical standard of Methyl p-methoxyhydrocinnamate (HY-N3290). This product is intended for research and analytical applications. Methyl p-methoxyhydrocinnamate is extracted from in liquid culture by the blue stain fungus Ophiostoma crassioaginata .

Cat. No.	Product Name	Type

HY-D0003

**Methyl Blue**	Fluorescent Dyes
Methyl blue belongs to the group of triaminotriphenylmethane dyes. Methyl blue is widely used as antiseptic dye in polychrome staining method and has applications in histological and microbiological staining solutions. Methyl blue has been used as a model to study the effect of various catalysts on photodegradation of dyes .

HY-D1416

HMBR 1 Publications Verification	Fluorescent Dyes
HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability .

HY-D0026

AMCA,SE 7-Amino-4-Methyl-3-coumarinacetic acid N-succinimidyl ester	Fluorescent Dyes
AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a bright blue fluorescent dye. AMCA,SE reacts with amino groups and is excited by ultraviolet light. AMCA,SE can be used for amine reactive labeling (Ex/Em = 354/440 nm) .

Cat. No.	Product Name	Type

HY-15932

TOOS TOOS sodium salt	Biochemical Assay Reagents
TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .

TOOS

TOOS sodium salt

Biochemical Assay Reagents

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .

Methyl p-methoxyhydrocinnamate Methyl p-methoxyphenylpropionate	Structural Classification Natural Products Microorganisms Source Classification	Others
Methyl p-methoxyhydrocinnamate is extracted from in liquid culture by the blue stain fungus Ophiostoma crassioaginata .

3,6-Dimethylundecane	Structural Classification Natural Products Animals Source Classification	Endogenous Metabolite
3,6-Dimethylundecane is a type of di-methyl alkanoid compound. 3,6-Dimethylundecane is one of the various branched alkanes identified in the metabolic products of the desert blue-green algae Microcoleus vaginatus .

Methyl p-methoxyhydrocinnamate (Standard) Methyl p-methoxyphenylpropionate (Standard)	Structural Classification Natural Products Microorganisms Source Classification	Others Reference Standards
Methyl p-methoxyhydrocinnamate (Standard) (Methyl p-methoxyphenylpropionate (Standard)) is the analytical standard of Methyl p-methoxyhydrocinnamate (HY-N3290). This product is intended for research and analytical applications. Methyl p-methoxyhydrocinnamate is extracted from in liquid culture by the blue stain fungus Ophiostoma crassioaginata .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Methyl Blue

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

NaturalProducts

Natural
Products