6 Results for "

Methyl-beta-cyclodextrin

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Methyl-beta-cyclodextrin" in MCE Product Catalog:

114
Methyl-β-cyclodextrin
Methyl-β-cyclodextrin
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114 Publications Verification
Cat. No.: HY-101461
CAS No.: 128446-36-6
Purity:  99.95%
Synonyms: Methyl-beta-cyclodextrin
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .
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92
Cholesterol (Water Soluble)
Cholesterol (Water Soluble)
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92 Cited Publications
Cat. No.: HY-N0322A
Category:  

Other Diseases Endogenous metabolite Disease Research Fields Steroids

Target:  

Liposome

Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
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1
Astressin 2B
Astressin 2B
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1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
Target:  

CRFR

Research Areas:  

Neurological Disease Inflammation/Immunology

Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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1
Astressin 2B TFA
Astressin 2B TFA
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1 Cited Publications
Cat. No.: HY-P1108A
Target:  

CRFR

Research Areas:  

Neurological Disease Inflammation/Immunology

Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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DM-β-CD
DM-β-CD
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Cat. No.: HY-137234
CAS No.: 51166-71-3
Purity:  99.9%
Synonyms: 2,6-Di-O-Methyl-β-cyclodextrin
DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
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Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin
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Cat. No.: HY-W145501
CAS No.: 55216-11-0
Synonyms: TriMethyl-beta-cyclodextrin
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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