3 Results for "

Midostaurin-d5

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Midostaurin-d5" in MCE Product Catalog:

Cat. No.: HY-10230S
Purity:  ≥98.0%
Synonyms: PKC412-d5; CGP 41251-d5
Midostaurin-d5 (PKC412-d5) is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM .
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Cat. No.: HY-108263S
Synonyms: CGP52421-d5
3-Hydroxy Midostaurin-d5 is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively .
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Cat. No.: HY-129491S
CAS No.: 2699608-28-9
Synonyms: CGP62221-d5; O-Desmethyl PKC412-d5
O-Desmethyl Midostaurin-d5 is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism .
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