24 Results for "

N-Ethylmaleimide

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "N-Ethylmaleimide" in MCE Product Catalog:

46
46 Cited Publications
Cat. No.: HY-D0843
CAS No.: 128-53-0
Synonyms: NEM
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .
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1
1 Cited Publications
Cat. No.: HY-134124
CAS No.: 92614-59-0
Purity:  95.8%
Research Areas:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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Cat. No.: HY-D0843S
CAS No.: 360768-37-2
Synonyms: NEM-d5
N-Ethylmaleimide-d5 is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor . N-ethylmaleimide specific inhibits phosphate transport in mitochondria . N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor .
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Cat. No.: HY-E70110
CAS No.: 37288-54-3
Research Areas:  

Others

Endo-1,4-β-mannanase is an important catalyst that randomly cleaves the β-1,4-linkages in the main chain of mannan, releasing short-chain β-1,4-mannan and mannose. The catalytic activity of Endo-1,4-β-mannanase toward locust bean gum is enhanced by Mn 2+, Co 2+, Ca 2+, Ba 2+, Triton X-100, sodium azide and N-ethylmaleimide, completely inhibited by Hg 2+ and N-bromosuccinimide, and partially inhibited by EDTA and Cu 2+. Endo-1,4-β-mannanase can be used in studies related to plant hemicellulose degradation, biomass saccharification, elimination of anti-nutritional factors in feed, and manno-oligosaccharide prebiotics .
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Cat. No.: HY-W585865
CAS No.: 112710-84-6
Synonyms: UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris
UDP-3-O-acyl-GlcNAc Tris (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris) serves as a deacetylation substrate and biosynthetic intermediate in the biosynthetic pathways of lipid A and Kdo2-lipid A in Escherichia coli. UDP-3-O-acyl-GlcNAc Tris undergoes enzymatic deacetylation via LpxC to produce UDP-3-O-[(R)-3-hydroxymyristoyl]glucosamine and release acetate. UDP-3-O-acyl-GlcNAc Tris accumulates in Escherichia coli extracts in the absence of [(R)-3-hydroxymyristoyl]-acyl carrier protein. UDP-3-O-acyl-GlcNAc Tris can be used in studies related to Gram-negative shock .
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Cat. No.: HY-D2315
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
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Cat. No.: HY-D0843R
CAS No.: 128-53-0
Synonyms: NEM (Standard)
Bayogenin (Standard) is the analytical standard of Bayogenin. This product is intended for research and analytical applications. Bayogenin is an alfalfa saponin, shows moderate potency of glycogen phosphorylase inhibition .
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Cat. No.: HY-P3066
CAS No.: 77453-01-1
Synonyms: d(CH2)5Tyr(Et)VAVP
Target:  

Vasopressin Receptor

Research Areas:  

Metabolic Disease

SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
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Cat. No.: HY-P5826
CAS No.: 126050-26-8
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. The formation of dynorphin B (1-9) is blocked by N-ethylmaleimide (NEM), a non-selective inhibitor of cysteine peptidases .
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Cat. No.: HY-P4110
Target:  

iGluR

TAT-NSF222 Fusion Peptide is a fusion polypeptide with two domains, a TAT domain, which enters cells through macropinocytosis, and an NSF domain that inhibits N-ethylmaleimide-sensitive factor (NSF). TAT-NSF222 Fusion Peptide is an exocytosis inhibitor .
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Cat. No.: HY-P10828
CAS No.: 1260620-30-1
Target:  

Virus Protease

Research Areas:  

Infection Inflammation/Immunology

MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
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Cat. No.: HY-P1399
CAS No.: 1423381-07-0
Synonyms: Myr-Pep2m
Target:  

PKC

Research Areas:  

Neurological Disease

Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
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Cat. No.: HY-P1399A
Synonyms: Myr-Pep2m TFA
Target:  

PKC

Research Areas:  

Neurological Disease

Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
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Cat. No.: HY-P1057
CAS No.: 243843-43-8
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity [1] [2] [3] [4] [5] [6].
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Cat. No.: HY-P4756
CAS No.: 282725-67-1
Target:  

Inhibitory Antibodies

Research Areas:  

Others

N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P76504
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NAPG; SNAP-Gamma; NSF Attachment Protein Gamma; Soluble NSF Attachment Protein; Gamma-Soluble NSF Attachment Protein; Gamma SNAP; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Gamma; GAMMASNAP; N-Ethylmaleimide-Sensitive Factor Attachment Protein
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P71326
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NAPA; N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha; NSF Attachment Protein Alpha; Alpha Soluble NSF Attachment Protein; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Alpha; Alpha SNAP; Alpha-Soluble NSF Attachment Protein; Alpha-SNAP
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P811898
Synonyms: NAPB; NSF Attachment Protein Beta; SNAPB; SNAP-BETA; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Beta; Beta-Soluble NSF Attachment Protein; N-Ethylmaleimide-Sensitive Factor Attachment Protein Beta; Beta Soluble NSF Attachment Protein; SNAP-Beta; DEE107

Host:  

Mouse

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811898A
Synonyms: NAPB; NSF Attachment Protein Beta; SNAPB; SNAP-BETA; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Beta; Beta-Soluble NSF Attachment Protein; N-Ethylmaleimide-Sensitive Factor Attachment Protein Beta; Beta Soluble NSF Attachment Protein; SNAP-Beta; DEE107

Host:  

Mouse

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P1058
CAS No.: 243843-42-7
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep2m is a peptide receptor inhibitor. Pep2m inhibits the interaction between the C-terminus of the AMPA-type glutamate receptor (GluA2) subunit and N-ethylmaleimide-sensitive fusion protein (NSF). Pep2m prevents synaptic long-term depression (LTD). Pep2m can reduce postsynaptic currents in neurons, AMPA-mediated currents in cultured hippocampal neurons, and AMPA receptor surface expression [1] [2] [3] [4] [5].
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