4 Results for "

N0774

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "N0774" in MCE Product Catalog:

18
18 Cited Publications
Cat. No.: HY-101254
CAS No.: 117946-91-5
Purity:  100.0%
Synonyms: N-0774
Target:  

Melatonin Receptor

Research Areas:  

Neurological Disease

Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole preferentially targets MT2 (Mel1b) over MT1 (Mel1a) with Ki values of 10.2 and 158 nM for human MT2 and MT1, respectively. Luzindole suppresses experimental autoimmune encephalomyelitis (EAE), and exerts antidepressant-like activity .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N0774
CAS No.: 486-21-5
Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells . Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation .
loading...
    loading...
Cat. No.: HY-N0774R
CAS No.: 486-21-5
Isofraxidin (Standard) is the analytical standard of Isofraxidin. This product is intended for research and analytical applications. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells . Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation .
loading...
    loading...
Cat. No.: HY-101254R
CAS No.: 117946-91-5
Synonyms: N-0774 (Standard)
Luzindole (Standard) is the analytical standard of Luzindole. This product is intended for research and analytical applications. Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole preferentially targets MT2 (Mel1b) over MT1 (Mel1a) with Ki values of 10.2 and 158 nM for human MT2 and MT1, respectively. Luzindole suppresses experimental autoimmune encephalomyelitis (EAE), and exerts antidepressant-like activity .
loading...
    loading...