1 Result for "

NF279

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NF279" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-D0976
CAS No.: 202983-32-2
Research Areas:  

Infection

NF279 is a selective P2X1 receptor antagonist and NTPDase inhibitor, with a P2X1 IC50 value of 19 nM. NF279 suppresses GABA-evoked currents, reduces ATP-excited respiratory activity, alters hypoglossal nerve burst parameters, and blocks CXCR4, CCR5, CXCR3, and CXCR7-mediated calcium responses. NF279 arrests HIV-1 fusion downstream of CD4 binding, inhibits R5- and X4-tropic HIV-1 strains. NF279 can be used for the research of HIV-1 infection .
loading...
    loading...