5 Results for "

NIS

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "NIS" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-N6791
CAS No.: 126643-37-6
KT5823, a selective the cGMP-dependent protein kinase (PKG) inhibitor with an Ki value of 0.23 μM, it also inhibits PKA and PKC with Ki values of 10 μM and 4 μM, respectively. KT5823 is a Staurosporine-related protein kinase inhibitor, increases thyroid-stimulating hormone-induced (Na +/I - symporter) NIS expression, and iodide uptake in thyroid cells. KT5823 arrests cells after the G0/G1 boundary and causes increases in the levels of apoptotic DNA fragmentation .
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Cat. No.: HY-P990009
CAS No.: 2649854-92-0
Synonyms: NIS-793

Research Areas:  

Cancer

Nisevokitug (NIS-793) is a humanized IgG2λ monoclonal antibody and an inhibitor of the TGF-β signaling pathway. Nisevokitug blocks the binding of TGF-β to the membrane-bound TGF-βR1/TGF-βR2 receptors, inhibits both Smad-dependent and Smad-independent downstream cascade signaling, downregulates fibrosis-related genes, and reverses the TGF-β-mediated immunosuppressive microenvironment. Nisevokitug can be used in the research of diseases such as pancreatic ductal adenocarcinoma, colorectal cancer, myelofibrosis, and myelodysplastic syndrome .
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Cat. No.: HY-114994
CAS No.: 541535-31-3
Purity:  ≥98.0%
Target:  

TSH Receptor

Research Areas:  

Endocrinology

MS437 is a potent TSH receptor (TSHR) stimulator with an EC50 value of 13x10 -8 M. MS437 shows potent activation of G, Gαq and 12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions .
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Cat. No.: HY-RS13291
Research Areas:  

Others

SLC5A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC5A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N0229S
CAS No.: 285977-86-8
Synonyms: L-2-Aminopropionic acid-2-13C,15N
L-Alanine-2- 13C, 15Nis the 13C-labeled and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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