541535-31-3
Chemical Structure
MS437
- CAS No.: 541535-31-3
- Formula:C22H24N2O
- Molecular Weight:332.44
IUPAC Name: N,N-diisopropyl-2-phenylquinoline-4-carboxamide
InChIKey: LXECNSUVDZQPHW-UHFFFAOYSA-N
SMILES: O=C(C1=C2C(C=CC=C2)=NC(C3=CC=CC=C3)=C1)N(C(C)C)C(C)C
Biological Activity: MS437 is a potent TSH receptor (TSHR) stimulator with an EC50 value of 13x10-8 M. MS437 shows potent activation of Gsα, Gαq and Gα12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions[1].
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MS437 | 98.0% | MS437 is a potent TSH receptor (TSHR) stimulator with an EC50 value of 13x10-8 M. MS437 shows potent activation of Gsα, Gαq and Gα12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions. | ||||||||||||||||||||
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Keywords