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NKp46 receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD20 (1) Interleukin Related (1)
By Research Areas:	Cancer (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-P992074

Zemlikafusp alfa IPH6501	CD20 Interleukin Related	Cancer
Zemlikafusp alfa (IPH6501) is a tetra-specific NK cell engager that targets CD20, CD16a, NKp46 and carries an IL-2 variant. Zemlikafusp alfa (IPH6501) is used in research for the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma .

Cat. No.	Nombre del producto	Target	Research Area	Image

HY-P992074

Zemlikafusp alfa IPH6501	CD20 Interleukin Related	Cancer
Zemlikafusp alfa (IPH6501) is a tetra-specific NK cell engager that targets CD20, CD16a, NKp46 and carries an IL-2 variant. Zemlikafusp alfa (IPH6501) is used in research for the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma .

Species:	Human (3) Rat (1) Mouse (1)
Tag:	His (1) Avi (1) Fc (4)
Source:	HEK293 (5)

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P70562

	NKp46/NCR1 Protein, Mouse (HEK293, Fc) Activating receptor1; mAR-1; Lymphocyte antigen94; Naturalkiller cell p46-related protein; NK-p46; NKp46; mNKp46	Mouse	HEK293
	NKp46/NCR1 Protein, a cytotoxicity-activating receptor, boosts activated natural killer (NK) cells' efficacy in eliminating tumor cells.Its interaction with CD3Z and FCER1G suggests a potential role in aiding NK cells in recognizing and destroying cancerous cells.NKp46/NCR1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived NKp46/NCR1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76514

	NKp46/NCR1 Protein, Rat (HEK293, Fc) Activating receptor1; mAR-1; Lymphocyte antigen94; Naturalkiller cell p46-related protein; NK-p46; NKp46; mNKp46	Rat	HEK293
	The NKp46/NCR1 protein is a key cytotoxic activating receptor that increases the efficiency of activated natural killer (NK) cells, particularly in targeting tumor cell lysis. Through interactions with CD3Z and FCER1G, NKp46/NCR1 orchestrates important connections that enhance the ability of NK cells to destroy tumor cells. NKp46/NCR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived NKp46/NCR1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70174

	NKp46/NCR1 Protein, Human (HEK293, Fc) rHuNatural Cytotoxicity Triggering receptor 1/NCR1, Fc; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD335; NCR1; LY94;	Human	HEK293
	NKp46/NCR1 Protein is a major NK cell-activating receptor that is involved in the elimination of target cells and recognizing a wide range of tumors, viruses, and bacteria. NKp46 forms microclusters structures at the immune synapse between NK cells and target cells. Over-expression of human NKp46 is correlated with increased accumulation of F-actin mesh at the immune synapse. NKp46 signaling directly regulates the NK lytic immune synapse from early formation to late function. NKp46/NCR1 Protein, Human (HEK293, Fc) is the recombinant human-derived NKp46/NCR1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704824

	NKp46/NCR1 Protein, Human (HEK293, Llama Fc) rHuNatural Cytotoxicity Triggering receptor 1/NCR1, Fc; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD335; NCR1; LY94;	Human	HEK293
	NKp46/NCR1 protein, a cytotoxicity-activating receptor on natural killer (NK) cells, potentially enhances their efficacy in tumor cell lysis. Interacting with CD247 and FCER1G, NKp46/NCR1 plays a pivotal role in signaling pathways associated with NK cell activation and cytotoxicity. It contributes to the regulatory network for recognizing and eliminating target cells, emphasizing its importance in immune surveillance and anti-tumor responses. NKp46/NCR1 Protein, Human (HEK293, Llama Fc) is the recombinant human-derived NKp46/NCR1 protein, expressed by HEK293, with C-Llama Fc labeled tag.

HY-P705169

	NKp46/NCR1 Protein, Human (Biotinylated, HEK293, His-Avi) rHuNatural Cytotoxicity Triggering receptor 1/NCR1, Fc; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD335; NCR1; LY94;	Human	HEK293

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Host:	Rabbit (2)
Reactivity:	Human (2)
Application:	IHC-P (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2) Biotin (1)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

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HY-P81447

	NCR1 Antibody (YA1192) natural cytotoxicity triggering receptor 1; LY94; CD335; NKp46; NK-p46	IHC-P	Human
	NCR1 Antibody (YA1192) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCR1.

HY-P81447A

	NCR1 Antibody (YA1192)(PBS only) natural cytotoxicity triggering receptor 1; LY94; CD335; NKp46; NK-p46	IHC-P	Human
	NCR1 Antibody (YA1192) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCR1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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