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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
OF1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "OF1" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
OF-1, a chemical probe, is a potent pan-BRPF bromodomain (BRD) inhibitor, with IC50 values of 270 nM, 1.2 μM for TRIM24 and BRPF1B, respectively [1] .
Cat. No.: HY-132485S
CAS No.: 1190008-84-4
Cat. No.: HY-P75672
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CHEK1; Non-Specific Serine/Threonine Protein Kinase; Checkpoint Kinase 1; Checkpoint, S. Pombe, Homolog OF, 1; CHK1; CHK1 (Checkpoint, S.Pombe) Homolog; Serine/Threonine-Protein Kinase Chk1; CHK1 Checkpoint Homolog (S. Pombe); CHK1 Checkpoint Homolog; OZE
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P74253
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CHEK1; Non-Specific Serine/Threonine Protein Kinase; Checkpoint Kinase 1; Checkpoint, S. Pombe, Homolog OF, 1; CHK1; CHK1 (Checkpoint, S.Pombe) Homolog; Serine/Threonine-Protein Kinase Chk1; CHK1 Checkpoint Homolog (S. Pombe); CHK1 Checkpoint Homolog; OZE
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P70210
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FZD1; DKFZp564G072; Frizzled Class Receptor 1; FzE1; Frizzled-1; Fz-1; Hfz1; Frizzled Homolog 1 (Drosophila); Frizzled 1, Seven Transmembrane Spanning Receptor; Frizzled (Drosophila) Homolog 1; Frizzled, Drosophila, Homolog OF, 1; Frizzled Homolog 1; Friz
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P86909
Synonyms: HOME1_HUMAN antibody; Homer antibody; HOMER 1A antibody; HOMER 1B antibody; HOMER 1C antibody; Homer homolog 1 (Drosophila) antibody; homer homolog 1 antibody; Homer protein homolog 1 antibody; homer scaffolding protein 1 antibody; Homer, Drosophila, homolog OF, 1 antibody; HOME1_HUMAN antibody; Homer antibody; HOMER 1A antibody; HOMER 1B antibody; HOMER 1C antibody; Homer homolog 1 (Drosophila) antibody; homer homolog 1 antibody; Homer protein homolog 1 antibody; homer scaffolding protein 1 antibody; Homer, Drosophila, homolog OF, 1 antibody; Homer, neuronal immediate early gene, 1 antibody; Homer-1 antibody; Homer1 antibody; HOMER1A antibody; HOMER1B antibody; HOMER1C antibody; SYN47 antibody; Ves 1 antibody;
Cat. No.: HY-P85913
Synonyms: 55 kDa actin bundling protein; 55 kDa actin-bundling protein; Actin bundling protein; actin bundling protein, 55-KD; FAN 1; FAN1; Fascin 1; Fascin actin bundling protein 1; Fascin; Fascin homolog 1 actin bundling protein; Strongylocentrotus purpuRatus; Fascin homolog 1; Fascin, sea urchin, homolog OF, 1; Fascin1; FLJ38511; FSCN 1; FSCN1; FSCN1_HUMAN; HSN; p55; Singed; Drosophila; like; sea urchin fascin homolog like; Singed drosophila homolog like; Singed like; fascin homolog sea urchin; Drosophila; Singed like; fascin homolog sea urchin; Singed like protein; Singed, drosophila, homolog OF; Singed-like protein; SNL; Strongylocentrotus purpuRatus
Cat. No.: HY-181960
CAS No.: 914302-78-6
Target:
Research Areas:
BP1.3656B is a selective, orally active, blood-brain barrier-permeable histamine H3 receptor (histamine H3 receptor) inverse agonist/antagonist, with a KB value of 0.08 nM for antagonizing agonist-induced activity and an IC50 value of 0.38 nM for directly inhibiting the basal activity of the receptor. BP1.3656B reduces alcohol consumption, alcohol-seeking behavior, alcohol self-administration, motivation to drink, alcohol relapse, alcohol-induced hyperlocomotion, and binge alcohol intake. BP1.3656B is applicable for the research of alcohol use disorder [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
