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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
OPN4
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "OPN4" in MCE Product Catalog:
2
2 Cited Publications
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AA92593 is a selective and competitive melanopsin OPN4 antagonist .
Cat. No.: HY-RS09799
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OPN4 Human Pre-designed siRNA Set A contains three designed siRNAs for OPN4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27301
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Opn4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Opn4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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AA41612 is a melanopsin (Opn4) inhibitor with an IC50 of 15.8 nM, a Ki of 0.43 nM, and a Kd of 0.28 nM. AA41612 competes with retinal for binding to melanopsin, blocks melanopsin activation, and inhibits melanopsin-mediated phototransduction processes without affecting rod- and cone-mediated responses. AA41612 attenuates light-induced melanopsin photocurrents, reduces light-induced cytoplasmic calcium elevation, and weakens high-irradiance pupillary light reflex in mice with induced classical photoreceptor degeneration. AA41612 can be used in studies related to migraine and photophobia .
Cat. No.: HY-RS20787
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Opn4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Opn4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702401
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Melanopsin; Opsin-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
