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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Ossification
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Ossification" in MCE Product Catalog:
3
3 Cited Publications
Research Areas:
CD1530 is an orally active, selective RARγ agonist and antibacterial agent. CD1530 reduces Smad1/5/8 phosphorylation and overall Smad levels. CD1530 reduces β-catenin, MMP9 protein, and ROS levels. CD1530 exhibits activities such as inhibiting heterotopic ossification, promoting Achilles tendon healing, and inhibiting muscle fatty infiltration. CD1530 can be used in the research of orthopedic diseases (such as heterotopic ossification, Achilles tendon injury), muscle diseases (such as muscle fatty infiltration-related diseases) .
Cat. No.: HY-N0754
CAS No.: 877822-40-7
Cat. No.: HY-P3637
CAS No.: 2640019-27-6
Target:
Research Areas:
Cat. No.: HY-124044
CAS No.: 1177148-36-5
Target:
Research Areas:
ML 086 is a highly selective PHOSPHO1 phosphatase inhibitor (IC50=0.14 μM). ML 086 is promising for research of hereditary vascular calcification disorders (e.g., generalized arterial calcification of infancy) and spinal ligament ossification .
Cat. No.: HY-32343S
CAS No.: 1440957-55-0
Synonyms: (24R)-24,25-Dihydroxyvitamin D3-d6
Cat. No.: HY-174704
Human FGF18 mRNA encodes the human fibroblast growth factor 18 (FGF18) protein, a member of the fibroblast growth factor (FGF) family. FGF18 probably plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. It is also required for normal ossification and bone development.
Cat. No.: HY-108527R
CAS No.: 107430-66-0
Target:
Reference Standards RAR/RXR Bacterial TGF-beta/Smad β-catenin MMP Reactive Oxygen Species (ROS)
Research Areas:
CD1530 (Standard) is the analytical standard of CD1530 (HY-108527). This product is intended for research and analytical applications. CD1530 is an orally active, selective RARγ agonist and antibacterial agent. CD1530 reduces Smad1/5/8 phosphorylation and overall Smad levels. CD1530 reduces β-catenin, MMP9 protein, and ROS levels. CD1530 exhibits activities such as inhibiting heterotopic ossification, promoting Achilles tendon healing, and inhibiting muscle fatty infiltration. CD1530 can be used in the research of orthopedic diseases (such as heterotopic ossification, Achilles tendon injury), muscle diseases (such as muscle fatty infiltration-related diseases) .
Cat. No.: HY-W142457
CAS No.: 18479-58-8
Target:
Research Areas:
Dihydromyrcenol is an orally active flavor ingredient and Antifungal agent. Dihydromyrcenol acts as a toxicant. Dihydromyrcenol induces phototoxicity-related growth inhibition in Bakers' Yeast. In pregnant rats, Dihydromyrcenol causes threshold maternal toxicity by reducing feed consumption and body weight gain, and also induces threshold developmental toxicity by decreasing fetal body weight, inhibiting ossification of metatarsal bones in the hind paws, increasing the number of extra thoracic vertebrae ribs, and altering vertebral counts .
Cat. No.: HY-L131
984 compounds
Ossification is a tightly regulated process, performed by specialized cells called osteoblasts. Dysregulation of this process may cause inadequate or excessive mineralization of bones or ectopic calcification, all of which have grave consequences for human health.
Osteoblasts play important roles in the process of osteogenesis and prevention of osteonecrosis. Osteoblast formation and bone formation are regulated by hormones, growth factors, cytokines, etc.
MCE offers a unique collection of 984 bone formation compounds with identified and potential inducing osteogenesis activity. MCE bone formation compound library is a useful tool for the study of bone disease drugs and pharmacology.
Cat. No.: HY-P74355
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CANT1; Apyrase Homolog; Calcium Activated Nucleotidase 1; Micromelic Dwarfism With Vertebral And Metaphyseal Abnormalities And Advanced Carpotarsal Ossification; SCAN-1; Ca2+-Dependent Endoplasmic Reticulum Nucleoside Diphosphatase; SHAPY; Soluble Calcium
Species:
Human
Source:
HEK293
Cat. No.: HY-P74356
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CANT1; Apyrase Homolog; Calcium Activated Nucleotidase 1; Micromelic Dwarfism With Vertebral And Metaphyseal Abnormalities And Advanced Carpotarsal Ossification; SCAN-1; Ca2+-Dependent Endoplasmic Reticulum Nucleoside Diphosphatase; SHAPY; Soluble Calcium
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
