153 Results for "

P.aeruginosa

" in MedChemExpress (MCE) Product Catalog:
Products (153)

153 Results for "P.aeruginosa" in MCE Product Catalog:

38
38 Publications Verification
Referencia número: HY-B1369A
No. CAS: 64221-86-9
Synonyms: N-Formimidoyl thienamycin; MK0787
Target:  

Antibiotic Bacterial

Áreas de investigación:  

Infection

Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
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38
38 Publications Verification
Referencia número: HY-B1369
No. CAS: 74431-23-5
Synonyms: N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate
Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
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3
3 Cited Publications
Referencia número: HY-P1674A
No. CAS: 3053070-05-3
Synonyms: POL7080 TFA
Target:  

Bacterial Antibiotic

Áreas de investigación:  

Infection

Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .
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2
2 Cited Publications
Referencia número: HY-130055
No. CAS: 341-88-8
Pureza:  99.19%
HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III . HQNO is a potent inhibitor of mitochondrial NDH-2 in many species .
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2
2 Cited Publications
Referencia número: HY-114544A
No. CAS: 168982-69-2
Pureza:  ≥98.0%
Synonyms: OdDHL
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
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2
2 Cited Publications
Referencia número: HY-P1633
No. CAS: 168831-77-4
Synonyms: PG1
Protegrin-1 is an orally active antibacterial peptide. Protegrin-1 activates ERK, COX2, NFκB, inhibits Apoptosis, and NO production. Protegrin-1 has antibacterial activity against S. aureus, E. faecium, E. coli, P. aeruginosa and K. Pneumoniae, with MBC values between 10 and 20 µM. Protegrin-1 has antiviral activity against dengue NS2B-NS3. Protegrin-1 has anti-inflammatory activity. Protegrin-1 is used in the study of inflammatory diseases and infections .
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1
1 Cited Publications
Referencia número: HY-N4136
No. CAS: 25694-72-8
Synonyms: Veronicastroside
Lonicerin (Veronicastroside) is a flavonoid with multiple biological activities. Lonicerin inhibits xanthine oxidase with an IC50 of 37.4 µg/mL. Lonicerin inhibits alginate secretion protein (AlgE). Lonicerin inhibits P. aeruginosa and C. albicans. Lonicerin has anti-inflammatory, anti-arthritic, antioxidant, antifungal, anti-bacterial, and neuroprotective properties .
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1
1 Cited Publications
Referencia número: HY-A0214
No. CAS: 8068-28-8
Synonyms: Colistimethate sodium
Target:  

Bacterial Antibiotic

Áreas de investigación:  

Infection

Colistin methanesulfonate sodium salt exhibits MIC values ranged from 4 to 16 mg/liter against susceptible strains (P. aeruginosa) .
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1
1 Cited Publications
Referencia número: HY-N2036
No. CAS: 740-33-0
Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with ?anti-EV71 activity. Mosloflavone? inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation.
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1
1 Cited Publications
Referencia número: HY-D1056E
Synonyms: LPS, from Pseudomonas aeruginosa (10)
Lipopolysaccharides from P. aeruginosa (Pseudomonas aeruginosa) 10 are lipopolysaccharide endotoxins and TLR4 activators derived from Pseudomonas aeruginosa 10, and are classified as S-type LPS. Lipopolysaccharides from P. aeruginosa 10 exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. The lipopolysaccharides of P. aeruginosa 10 have a fatty acid composition distinct from common enterobacteria, an exceptionally high degree of phosphorylation (triphosphate residues have been detected), and a unique outer region of the core oligosaccharide. Additionally, their O-specific side chains are typically rich in novel aminosugars. Lipopolysaccharides from P. aeruginosa 10 demonstrate susceptibility to viruses, with the level of susceptibility determined by the content of high molecular weight polysaccharides in their composition. The absence of high molecular weight polysaccharides increases their sensitivity to bacteriophages .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
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1
1 Cited Publications
Referencia número: HY-W094847
No. CAS: 112-95-8
Eicosane is an alkane with anti-microbial effects. Eicosane inhibits the growth of B. subtilis, E. coli and P. aeruginosa. Eicosane is used to form candles .
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1
1 Cited Publications
Referencia número: HY-B0724A
No. CAS: 163680-77-1
Synonyms: T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate
Áreas de investigación:  

Infection

Pazufloxacin mesylate is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin mesylate inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin mesylate exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin mesylate is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia .
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Referencia número: HY-162475
No. CAS: 2757070-32-7
Áreas de investigación:  

Infection

Fluorofolin is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.5 nM. Fluorofolin exhibits significant activity against P. aeruginosa .
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Referencia número: HY-N5127
No. CAS: 630-03-5
Nonacosane, isolated from Baphia massaiensis, exhibits weak activities against E. coli, B. subtilis, P. aeruginosa and S. aureus .
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Referencia número: HY-124819
No. CAS: 957471-96-4
Target:  

Bacterial

Áreas de investigación:  

Infection

D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively . D13-9001 exhibits antibiotic activities .
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Referencia número: HY-N10087
No. CAS: 550-43-6
Angustifoline, an alkaloid, can be isolated from Lupinus angustifolius L. alkaloid extract. Angustifoline exhibits antimicrobial activity. Angustifoline could have bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis .
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Referencia número: HY-19882
No. CAS: 941285-15-0
Target:  

Bacterial

Áreas de investigación:  

Infection

BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively .
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Referencia número: HY-P99214
No. CAS: 885053-97-4
Synonyms: KBPA101

Target:  

Bacterial

Áreas de investigación:  

Infection

Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of P. aeruginosa .
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Referencia número: HY-P5731
Target:  

Bacterial

Áreas de investigación:  

Infection

Bac7(1-35) is a proline-rich antimicrobial peptide. Bac7(1-35) efficiently binds to different regions of prokaryote ribosomes, leading to the inhibition of protein synthesis. Bac7(1-35) demonstrates in vitro activity against P. aeruginosa strains .
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Referencia número: HY-P3328A
Target:  

Bacterial

Áreas de investigación:  

Infection

MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
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