3 Results for "

P2281

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "P2281" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P2281A
Synonyms: Atrial natriuretic peptide (1-28) TFA
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) TFA inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) TFA increases cGMP levels in RMIC cells with an IC50 of 1.2 nM .
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Cat. No.: HY-P2281
CAS No.: 91917-63-4
Synonyms: Atrial natriuretic peptide (1-28)
Atrial natriuretic factor (1-28) (human, porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) increases cGMP levels in RMIC cells with an IC50 of 1.2 nM .
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Cat. No.: HY-118704
CAS No.: 1112994-35-0
Purity:  99.81%
Target:  

mTOR

Research Areas:  

Inflammation/Immunology Cancer

P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P2281 inhibits mTOR activity in colon cancer cells. P-2281 suppresses Dextran sulfate sodium salt (HY-116282C) (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis .
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