4 Results for "

PARPi

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "PARPi" in MCE Product Catalog:

Cat. No.: HY-120115
CAS No.: 1380359-84-1
Purity:  99.74%
Synonyms: Olaparib-bodipy FL
Target:  

PARP Fluorescent Dye

Research Areas:  

Cancer

PARPi-FL (Olaparib-bodipy FL) is a small-molecule fluorescent inhibitor of PARP1 that can specifically bind to PARP1. PARPi-FL can be used as a fluorescent imaging agent for tumor detection, diagnosis, and surgical guidance .
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Cat. No.: HY-155993
CAS No.: 3032451-66-1
Purity:  99.39%
Target:  

PARP

Research Areas:  

Cancer

YCH1899 is an orally active PARP inhibitor, with an IC50< 0.001 nM for PARP1/2. YCH1899 exhibits distinct antiproliferation activity against Olaparib (HY-10162)-resistant and Talazoparib (HY-16106)-resistant Capan-1 cells (Capan-1/OP and Capan-1/TP cells) , with IC50 values of 0.89 and 1.13 nM, respectively. YCH1899 has acceptable pharmacokinetic properties in rats .
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Cat. No.: HY-179219S
CAS No.: 3035072-99-9
RTx-303 is an orally active, selective DNA polymerase θ (Polθ) inhibitor (IC50 = 5.1 nM). RTx-303 exhibits significantly high cellular potency and strongly potentiates PARPi in BRCA1/2 mutant cells and patient-derived xenograft models. RTx-303 can be used for the study of BRCA2-mutated breast cancer .
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Cat. No.: HY-156982
CAS No.: 1919043-65-4
Research Areas:  

Cancer

Parpi is a PET radioactive tracer with low lipotropy. Parpi can be used as a tumor imaging agent .
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