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PEGylation

" in MedChemExpress (MCE) Product Catalog:

71

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57

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-166990

    MeO-PEG5000-Mal

    Biochemical Assay Reagents Others
    Methoxypolyethylene glycol maleimide 5000 (MeO-PEG-Mal) is a protein PEGylation reagent.
    Methoxypolyethylene glycol maleimide 5000
  • HY-147087

    Liposome Cancer
    YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .
    YSK 05
  • HY-W451406C

    PROTAC Linkers Others
    NH2-PEG2000-NH2 is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
    NH2-PEG2000-NH2
  • HY-166990B

    MeO-PEG2000-Mal

    Biochemical Assay Reagents Others
    Methoxypolyethylene glycol maleimide 2000 (MeO-PEG2000-Mal) is a protein PEGylation reagent .
    Methoxypolyethylene glycol maleimide 2000
  • HY-P11288A

    PACAP Receptor Apoptosis Cancer
    ANT308 TFA is a vasoactive intestinal polypeptide (VIP receptor) antagonist. ANT308 TFA significantly enhances the activation and proliferation of T cells. ANT308 TFA inhibits the migration and metastasis, induces apoptosis of melanoma tumor cells by inhibiting VIP-VPAC2 signaling and reducing the expression of MCAM and N-cadherin. ANT308 TFA can be used for the study of acute myeloid leukemia (AML) and uveal melanoma (UVM) .
    ANT308 TFA
  • HY-P11288

    PACAP Receptor Apoptosis Cancer
    ANT308 is a vasoactive intestinal polypeptide (VIP receptor) antagonist. ANT308 significantly enhances the activation and proliferation of T cells. ANT308 inhibits the migration and metastasis, induces apoptosis of melanoma tumor cells by inhibiting VIP-VPAC2 signaling and reducing the expression of MCAM and N-cadherin. ANT308 can be used for the studies of acute myeloid leukemia (AML) and uveal melanoma (UVM) .
    ANT308
  • HY-W1049092

    Biochemical Assay Reagents Others
    mPEG2000-N3 can be used to modify proteins, peptides, and other materials. The azide group can react with alkynes in aqueous solution catalyzed by copper. It can also be easily reduced to an amine group. PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins. mPEG2000-N3 can also inhibit the nonspecific binding of charged molecules to the modified surface .
    mPEG2000-N3
  • HY-140656H

    Biochemical Assay Reagents Others
    Biotin-PEG40000-Biotin can be used for crosslinking PEGylation by binding to two streptavidin and avidin. Biotin is conjugated to a linear PEG through a stable amide linker .
    Biotin-PEG40000-Biotin
  • HY-176509A

    Liposome Others
    DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .
    DSPE-PEG2000-CHO
  • HY-W020780C

    mPEG3400-Maleimide

    Biochemical Assay Reagents Others
    mPEG3400-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
    mPEG3400-Mal
  • HY-108790

    Peginterferon β-1a

    Apoptosis Neurological Disease Cancer
    Peginterferon beta-1a (Peginterferon β-1a) is the first pegylated interferon beta-1a molecule. Peginterferon beta-1a induces cancer cells apoptosis and shows anti-tumor activities in nude mice models. Peginterferon beta-1a can be used for the research of cancer and multiple sclerosis (RMS) .
    Peginterferon beta-1a
  • HY-155901

    Maleimide-NH-PEG2000-amine TFA

    Biochemical Assay Reagents Others
    Mal-NH-PEG2000-NH2TFA is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
    Mal-NH-PEG2000-NH2 TFA
  • HY-176509C

    Liposome Others
    DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .
    DSPE-PEG5000-CHO
  • HY-176509

    Liposome Others
    DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .
    DSPE-PEG1000-CHO
  • HY-174359C

    Biochemical Assay Reagents Others
    Alkyne-PEG5000-NH2 is an alkyne-functionalized bifunctional PEG derivative that can be used to modify proteins, peptides, and other materials. The alkyne group reacts with azides in aqueous solution in a copper-catalyzed manner. PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins .
    Alkyne-PEG5000-NH2
  • HY-174358D

    Biochemical Assay Reagents Others
    HOOC-PEG10000-COOH has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG10000-COOH is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .
    HOOC-PEG10000-COOH
  • HY-148154

    Drug Derivative Others
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6 (n=450) is an active compound. Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6 is a small molecule moiety for pegylation modification in Avacincaptad pegol (HY-147080) .
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6
  • HY-148153

    Drug Derivative Inflammation/Immunology
    C6-Amide-(PEG)n-CH3 (n=310) is an active compound. C6-Amide-(PEG)n-CH3 is a small molecule moiety for PEGylation in Egaptivon pegol (HY-147079) that can be used for the research of platelet dysfunction disorders .
    C6-Amide-(PEG)n-CH3
  • HY-W020780A

    mPEG350-Maleimide

    Biochemical Assay Reagents Others
    mPEG350-Mal is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
    mPEG350-Mal
  • HY-W020780B

    mPEG750-Maleimide

    Biochemical Assay Reagents Others
    mPEG750-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
    mPEG750-Mal
  • HY-144011

    Liposome Others
    DSPE-PEG-Cyanur ammonium is a PEG derivative containing cyanur functional group. DSPE-PEG-Cyanur ammonium can be used for PEGylation of protein under mild basic conditions. DSPE-PEG-Cyanur ammonium can be used for nanostructured lipid carrier .
    DSPE-PEG-Cyanur ammonium
  • HY-174358A

    Biochemical Assay Reagents Others
    HOOC-PEG2000-COOH has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG2000-COOH is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .
    HOOC-PEG2000-COOH
  • HY-174358E

    Biochemical Assay Reagents Others
    HOOC-PEG20000-COOH has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG20000-COOH is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .
    HOOC-PEG20000-COOH
  • HY-174359H

    Biochemical Assay Reagents Others
    Alkyne-PEG40000-NH2 is an alkyne-functionalized bifunctional PEG derivative that can be used to modify proteins, peptides, and other materials. The alkyne group reacts with azides in aqueous solution in a copper-catalyzed manner. PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins .
    Alkyne-PEG40000-NH2
  • HY-174359A

    Biochemical Assay Reagents Others
    Alkyne-PEG2000-NH2 is an alkyne-functionalized bifunctional PEG derivative that can be used to modify proteins, peptides, and other materials. The alkyne group reacts with azides in aqueous solution in a copper-catalyzed manner. PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins .
    Alkyne-PEG2000-NH2
  • HY-164076

    Biochemical Assay Reagents Others
    mPEG-Epoxide is an activated polyethylene glycol (mPEG) derivative, which is achieved by converting the hydroxyl groups of mPEG into reactive epoxy groups. mPEG-Epoxide is a mild PEGylation reagent that reacts with amino groups in peptides and proteins to form stable secondary amine bonds. mPEG-Epoxide can be used in protein engineering and biomaterials research .
    mPEG-Epoxide
  • HY-W1049075E

    Biochemical Assay Reagents Others
    mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
    mPEG-pALD (MW 2000)
  • HY-W1049075B

    Biochemical Assay Reagents Others
    mPEG10000-Pald is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
    mPEG10000-Pald
  • HY-W1049075D

    Biochemical Assay Reagents Others
    mPEG40000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
    mPEG40000-pALD
  • HY-161750

    PROTACs Anaplastic lymphoma kinase (ALK) Cancer
    PROTAC ALK degrader-2 (B1-PEG) is an ALK degrader based on PROTACs, with the DC50 of 45 nM in H3122 EML4-ALK DC50 (GSH+). PROTAC ALK degrader-2, through PEGylation, is engineered to self-organize into micelles in water and releases its active form in response to the tumor-specific high GSH environment .
    PROTAC ALK degrader-2
  • HY-176509D

    Liposome Others
    DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .
    DSPE-PEG10000-CHO
  • HY-W1049092H

    Biochemical Assay Reagents Others
    mPEG3400-N3 can be used to modify proteins, peptides, and other materials. The azide group can react with alkynes in aqueous solution catalyzed by copper. It can also be easily reduced to an amine group. PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins. mPEG3400-N3 can also inhibit the nonspecific binding of charged molecules to the modified surface .
    mPEG3400-N3
  • HY-176509B

    Liposome Others
    DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .
    DSPE-PEG3400-CHO
  • HY-W1049092E

    Biochemical Assay Reagents Others
    mPEG1000-N3 can be used to modify proteins, peptides, and other materials. The azide group can react with alkynes in aqueous solution catalyzed by copper. It can also be easily reduced to an amine group. PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins. mPEG1000-N3 can also inhibit the nonspecific binding of charged molecules to the modified surface .
    mPEG1000-N3
  • HY-176509H

    Liposome Others
    DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .
    DSPE-PEG40000-CHO
  • HY-W451406D

    PROTAC Linkers Others
    NH2-PEG10000-NH2 is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
    NH2-PEG10000-NH2
  • HY-W451406A

    PROTAC Linkers Others
    NH2-PEG5000-NH2 is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
    NH2-PEG5000-NH2
  • HY-W800717

    Biochemical Assay Reagents Others
    Tetra-(amido-PEG10-azide) is a branched PEG linker with four terminal azide groups. The azide groups enable PEGylation via Click Chemistry.
    Tetra-(amido-PEG10-azide)
  • HY-W800716

    Biochemical Assay Reagents Others
    Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine is a branched PEG linker with three terminal azide groups. The azide groups enable PEGylation via Click Chemistry.
    Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine
  • HY-W1123943A

    Biochemical Assay Reagents Others
    8-Arm-PEG600-Biotin is a multiarmed PEG derivative with biotin at each terminal of the eight arms. 8-Arm-PEG600-Biotin is for PEGylation by binding to streptavidin and avidin with high affinity and specificity .
    8-Arm-PEG600-Biotin
  • HY-W1123943

    Biochemical Assay Reagents Others
    8-Arm-PEG400-Biotin is a multiarmed PEG derivative with biotin at each terminal of the eight arms. 8-Arm-PEG400-Biotin is for PEGylation by binding to streptavidin and avidin with high affinity and specificity .
    8-Arm-PEG400-Biotin
  • HY-W1123943B

    Biochemical Assay Reagents Others
    8-Arm-PEG1000-Biotin is a multiarmed PEG derivative with biotin at each terminal of the eight arms. 8-Arm-PEG1000-Biotin is for PEGylation by binding to streptavidin and avidin with high affinity and specificity .
    8-Arm-PEG1000-Biotin
  • HY-W1123943H

    Biochemical Assay Reagents Others
    8-Arm-PEG10000-Biotin is a multiarmed PEG derivative with biotin at each terminal of the eight arms. 8-Arm-PEG10000-Biotin is for PEGylation by binding to streptavidin and avidin with high affinity and specificity .
    8-Arm-PEG10000-Biotin
  • HY-W1123943E

    Biochemical Assay Reagents Others
    8-Arm-PEG5000-Biotin is a multiarmed PEG derivative with biotin at each terminal of the eight arms. 8-Arm-PEG5000-Biotin is for PEGylation by binding to streptavidin and avidin with high affinity and specificity .
    8-Arm-PEG5000-Biotin
  • HY-W1123943D

    Biochemical Assay Reagents Others
    8-Arm-PEG3400-Biotin is a multiarmed PEG derivative with biotin at each terminal of the eight arms. 8-Arm-PEG3400-Biotin is for PEGylation by binding to streptavidin and avidin with high affinity and specificity .
    8-Arm-PEG3400-Biotin
  • HY-W1123943C

    Biochemical Assay Reagents Others
    8-Arm-PEG2000-Biotin is a multiarmed PEG derivative with biotin at each terminal of the eight arms. 8-Arm-PEG2000-Biotin is for PEGylation by binding to streptavidin and avidin with high affinity and specificity .
    8-Arm-PEG2000-Biotin
  • HY-W800688

    Biochemical Assay Reagents Others
    Acid-PEG5-Amide-Tri(3-methoxypropanamide-PEG4-Azide) Methane is a branched PEG linker with a terminal carboxylic acid group and three terminal azides. The azide groups enables PEGylation via Click Chemistry.
    Acid-PEG5-Amide-Tri (3-methoxypropanamide-PEG4-Azide) Methane
  • HY-W1048860B

    Biochemical Assay Reagents Others
    4-Arm PEG10000-alkyne is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
    4-Arm PEG10000-alkyne
  • HY-W1048860D

    Biochemical Assay Reagents Others
    4-Arm PEG40000-alkyne is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
    4-Arm PEG40000-alkyne
  • HY-W1048860A

    Biochemical Assay Reagents Others
    4-Arm PEG5000-alkyne is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
    4-Arm PEG5000-alkyne

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