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Results for "

PHA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (2) Apoptosis (4) Aurora Kinase (4) Autophagy (5) Bacterial (4) Bcr-Abl (1) Biochemical Assay Reagents (4) c-Kit (4) c-Met/HGFR (1) c-Myc (1) Caspase (1) CD3 (1) CDK (8) COX (1) CTLA-4 (1) Drug Isomer (1) Drug Metabolite (1) E1/E2/E3 Enzyme (1) Endogenous Metabolite (7) Environmental Pollutants (1) Flavivirus (1) Fluorescent Dye (3) Histone Methyltransferase (1) HIV (1) IKK (1) IMPDH (1) Integrin (1) Interleukin Related (2) Isotope-Labeled Compounds (1) JNK (1) Leukotriene Receptor (1) Lipoxygenase (2) Na+/K+ ATPase (1) nAChR (6) NF-κB (3) Nuclear Factor of activated T Cells (NFAT) (1) Parasite (2) PDGFR (4) Potassium Channel (1) Reactive Oxygen Species (ROS) (5) Reference Standards (9) Ser/Thr Kinase (1) Small Interfering RNA (siRNA) (1) VEGFR (4)
By Research Areas:	Cancer (20) Cardiovascular Disease (1) Infection (8) Inflammation/Immunology (15) Metabolic Disease (4) Neurological Disease (10)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7038

Phytohemagglutinin 5+ Cited Publications PHA-M	NF-κB COX Interleukin Related Reactive Oxygen Species (ROS)	Neurological Disease Inflammation/Immunology Cancer
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β .

HY-10179

Danusertib 5+ Cited Publications PHA-739358	Aurora Kinase Autophagy	Cancer
Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC₅₀ of 13, 79, and 61 nM for Aurora A, B, and C, respectively.

HY-11107

PHA-665752 10+ Cited Publications	c-Met/HGFR Autophagy Apoptosis	Cancer
PHA-665752 is a selective, ATP-competitive, and active-site inhibitor of the catalytic activity of c-Met kinase (K_i=4 nM; IC₅₀=9 nM). PHA-665752 exhibits >50-fold selectivity for c-Met compared with a panel of diverse tyrosine and serine-threonine kinases. PHA-665752 induces apoptosis and cell cycle arrest, and exhibits cytoreductive antitumor activity .

HY-13461

PHA-767491 4 Publications Verification CAY10572	CDK	Cancer
PHA-767491 is a dual Cdc7/Cdk9 inhibitor, with IC₅₀s of 10 nM and 34 nM, respectively.

HY-N7038A

Phytohemagglutinin P PHA-P	Others	Inflammation/Immunology
Phytohemagglutinin P (PHA-P) is a mitogen known to selectively stimulate cells of hematogenous or lymphoid monocytic origin .

HY-10424

Milciclib 5+ Cited Publications PHA-848125	CDK Autophagy	Cancer
Milciclib (PHA-848125) is a potent, ATP-competitive and dual inhibitor of CDK and Tropomyosin receptor kinase (TRK), with IC₅₀s of 45, 150, 160, 363, 398 nM and 53 nM for cyclin A/CDK2, cyclin H/CDK7, cyclin D1/CDK4, cyclin E/CDK2, cyclin B/CDK1 and TRKA, respectively.

HY-11001

PHA-793887 4 Publications Verification	CDK Apoptosis	Cancer
PHA-793887 is a potent, ATP-competitive CDK inhibitor, can inhibit Cdk2, Cdk1, Cdk4, and Cdk9 with IC₅₀s of 8 nM, 60 nM, 62 nM and 138 nM, respectively, and also inhibits glycogen synthase kinase 3β with an IC₅₀ of 79 nM.

HY-113004

3-Hydroxyvaleric acid	Endogenous Metabolite	Metabolic Disease
3-Hydroxyvaleric acid is a five-carbon ketone body byproduct that can undergo an anaplerotic reaction to replenish the intermediates of the tricarboxylic acid cycle. 3-Hydroxyvaleric acid is one of the important monomers for the synthesis of polyhydroxyalkanoates (PHA). PHA is a type of biodegradable plastic that is widely used in environmentally friendly packaging, disposable products, and medical materials .

HY-10330A

Toceranib phosphate SU11654 phosPHAte; PHA 291639E phosPHAte	PDGFR VEGFR c-Kit	Cancer
Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with K_is of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors .

HY-B1916

Acetylspiramycin 2 Publications Verification Spiramycin B; Spiramycin II; Foromacidin B	Antibiotic Bacterial Parasite	Infection
Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection .

HY-I0301

D-(+)-Glucono-1,5-lactone 1 Publications Verification Gluconic acid lactone	Environmental Pollutants Endogenous Metabolite Reactive Oxygen Species (ROS)	Others
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-10330

Toceranib SU11654; PHA 291639E	PDGFR VEGFR c-Kit	Cancer
Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with K_is of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors .

HY-13461A

PHA-767491 hydrochloride 4 Publications Verification CAY-10572 hydrochloride	CDK Apoptosis	Cancer
PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC₅₀s of 10 nM and 34 nM, respectively.

HY-NP0184

Phaseolus Vulgaris Leucoagglutinin (Biotinylated) PHA-L (Biotinylated)	Fluorescent Dye	Others
Phaseolus Vulgaris Leucoagglutinin (PHA-L) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Phaseolus Vulgaris Leucoagglutinin (PHA-L) Biotinylated is a biological material or organic compound that can be used in life science research .

HY-NP077

Phaseolus vulgaris leucoagglutinin PHA-L	Biochemical Assay Reagents	Neurological Disease
Phaseolus vulgaris leucoagglutinin (PHA-L) is a lectin, that can be extracted from red kidney beans (Phaseolus vulgaris). Phaseolus vulgaris leucoagglutinin can be used as an anterograde axonal tracer in neuroanatomical research to study the morphology of neurons, axons, and terminal structures in the nervous system .

HY-14180

PHA 408 1 Publications Verification	IKK	Inflammation/Immunology
PHA 408 (PHA-408) is a potent, selective and orally active IκB kinase-2 (IKK-2) inhibitor. PHA 408 is a powerful anti-inflammatory agent against lipopolysaccharide (LPS)- and cigarette smoke (CS)-mediated lung inflammation .

HY-105670

PHA-543613	nAChR	Neurological Disease
PHA-543613 is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a K_i of 8.8 nM. PHA-543613 displays selectivity for α7-nAChR over α3β4, α1β1γδ, α4β2 and 5-HT3 receptors . PHA-543613 can be used for the cognitive deficits of Alzheimer's disease and schizophrenia research .

HY-10178

PHA-680632	Aurora Kinase	Cancer
PHA-680632 is an aurora kinase inhibitor with IC₅₀s of 27, 135 and 120 nM for aurora A, B and C, respectively.

HY-162683

*(S)-PHA533533*	CDK E1/E2/E3 Enzyme	Neurological Disease
(S)-PHA533533 is a CDK2 and CDK5 inhibitor with blood-brain barrier permeability, with IC₅₀ values of 37 nM and 55 nM, respectively. (S)-PHA533533 effectively restores UBE3A expression by downregulating UBE3A-ATS and relieving the epigenetic silencing of paternal UBE3A in mature neurons. (S)-PHA533533 can be used for the research of Angelman syndrome .

HY-113058

3-Hydroxyoctanoic acid	Endogenous Metabolite	Metabolic Disease
3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

HY-N1196

Suberosin	NF-κB	Inflammation/Immunology
Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB .

HY-W009245

Bz-RS-iSer(3-Ph)-OMe	HIV	Infection Cancer
Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation .

HY-W010625

Lithium 2-hydroxypropanoate 35+ Cited Publications	Biochemical Assay Reagents	Neurological Disease Inflammation/Immunology
Lithium 2-hydroxypropanoate is a lithium salt. Lithium 2-hydroxypropanoate has immunomodulatory activity (slightly enhancing PHA (HY-N7038)-induced lymphocyte proliferation). Lithium 2-hydroxypropanoate can be used in antioxidant activity assays. Lithium 2-hydroxypropanoate can be used in the research of mental diseases .

HY-129674

PHA 568487 free base 1 Publications Verification	nAChR	Neurological Disease
PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor (α-7 nAchR) agonist. PHA 568487 free base reduces neuroinflammation .

HY-105670B

PHA-543613 dihydrochloride	nAChR	Neurological Disease
PHA-543613 dihydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a K_i value of 8.8 nM. PHA-543613 dihydrochloride displays selectivity for α7-nAChR over α3β4, α1β1γδ, α4β2 and 5-HT3 receptors . PHA-543613 dihydrochloride can be used for the cognitive deficits of Alzheimer's disease and schizophrenia research .

HY-W704598

Methyl 3-hydroxydodecanoate	Biochemical Assay Reagents Bacterial	Infection
Methyl 3-hydroxydodecanoate is a poly (3-hydroxyalkanoate) monomer. Methyl 3-hydroxydodecanoate can be produced with the involvement of Pseudomonas putida Bet001 .

HY-125090

PHA-680626	Aurora Kinase c-Myc Bcr-Abl Histone Methyltransferase Apoptosis	Cancer
PHA-680626 is an effective inhibitor of the interaction between Aurora-A and N-Myc. PHA-680626 inhibits kinase activity of AURKA and Bcr-Abl, and induces N-Myc degradation. PHA-680626 decreases phosphorylation of CrkL and histone H3. PHA-680626 shows anti-proliferative and pro-apoptotic activity on Imatinib (HY-15463)-resistant chronic myeloid leukemia cell lines and primary CD34+ cells .

HY-118917

VX-148	IMPDH	Inflammation/Immunology
VX-148 is an orally active immunosuppressant, which is a non-competitive inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor with K_i values for IMPDH Ⅱ and IMPDH Ⅰ of 6 and 14 nM respectively. VX-148 can significantly inhibit the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated by T-cell mitogen (PHA) or B-cell mitogen (SPAS). VX-148 has high selectivity for lymphocytes (such as L1210, Jurkat T cells, and Raji B cells), but has no significant toxicity to non-lymphoid cells. VX-148 can inhibit antibody responses in mouse models and significantly prolong the survival time of transplanted skin in allogeneic skin transplantation models. VX-148 can be used in the research of autoimmune diseases (such as rheumatoid arthritis, psoriasis) and organ transplantation anti-rejection .

HY-NP076

Phaseolus Vulgaris Erythroagglutinin PHA-E	Fluorescent Dye	Others
Phaseolus Vulgaris Erythroagglutinin (PHA-E) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Phaseolus Vulgaris Erythroagglutinin (PHA-E) is a biological material or organic compound that can be used in life science research .

HY-P99837

Dafsolimab SPV-T3a	CD3	Infection
Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .

HY-107666

PHA 568487	nAChR	Neurological Disease Inflammation/Immunology
PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor (α-7 nAchR) ^[2].PHA 568487 reduces neuroinflammation and oxidative stress . PHA-568487 has rapid brain penetration .

HY-155516

KV1.3-IN-1	Potassium Channel	Inflammation/Immunology
KV1.3-IN-1 (Compound trans-18) is a KV1.3 channel inhibitor (IC₅₀: 230 nM and 26.12 nM in Ltk cells and PHA-activated T-lymphocytes respectively). KV1.3-IN-1 impairs intracellular Ca ²⁺ signaling. KV1.3-IN-1 inhibits T-cell activation, proliferation, and colony formation .

HY-15503

PHA-690509	Caspase CDK Flavivirus	Infection
PHA-690509 is an anti-ZikV compound that inhibits ZikV replication. PHA-690509 is also a CDK inhibitor, and inhibits caspase-3 activity .

HY-P991566

KD6001	CTLA-4	Cancer
KD6001 is a humanized IgG1κ monoclonal antibody, targeting CTLA4. KD6001 significantly disrupts CTLA-4 interactions with CD80 (IC₅₀: 16 ng/mL) and CD86. KD6001 enhances IL-2 and IFNγ expression in PHA-activated human lymphocytes and exhibits potent antitumor effects. KD6001 effectively inhibits tumor growth in MC38, B16, and Hepa1-6 tumor mice model. KD6001 can be used for cancers research, such as advanced melanoma, hepatocellular carcinoma and liver cancer .

HY-117253

PHA-782584	Drug Metabolite	Cancer
PHA-782584 is a metabolite of sunitinib. Sunitinib is an oral multitargeted tyrosine kinase inhibitor with antitumor activities .

HY-105670A

PHA-543613 hydrochloride	nAChR	Neurological Disease
PHA-543613 hydrochloride is an oral or active α7 nAChR agonist with brain permeability, For α3β4, α1β1γδ, α4β2 and 5-HT3 receptors selective. PHA-543613 hydrochloride affects sensory gating and memory in an in vivo model of schizophrenia .

HY-162683A

*(R)-PHA533533*	CDK Drug Isomer	Cancer
(R)-PHA533533 is an inactive enantiomer (S)-PHA533533 (active enantiomer) (HY-162683). (S)-PHA533533 is a CDK2 inhibitor with antitumor activity .

HY-10424A

Milciclib maleate PHA-848125 maleate	Ser/Thr Kinase	Cancer
Milciclib (PHA-848125) maleate is a cyclin-dependent kinase inhibitor that impairs melanoma cell growth and modulates gene expression involved in cell cycle regulation. Milciclib maleate has been shown to significantly affect the expression of various genes, including down-regulating PTTG1, contributing to its antiproliferative activity. Milciclib maleate enhances sensitivity to treatment in p53 mutated melanoma cells when combined with PTTG1 silencing.

HY-NP0140

Phaseolus Vulgaris Leucoagglutinin (Fluorescein) PHA-L (Fluorescein)	Fluorescent Dye	Others
Phaseolus Vulgaris Leucoagglutinin (PHA-L) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Phaseolus Vulgaris Leucoagglutinin (PHA-L) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-10424R

Milciclib (Standard) PHA-848125 (Standard)	Reference Standards CDK Autophagy	Cancer
Milciclib (Standard) is the analytical standard of Milciclib. This product is intended for research and analytical applications. Milciclib (PHA-848125) is a potent, ATP-competitive and dual inhibitor of CDK and Tropomyosin receptor kinase (TRK), with IC50s of 45, 150, 160, 363, 398 nM and 53 nM for cyclin A/CDK2, cyclin H/CDK7, cyclin D1/CDK4, cyclin E/CDK2, cyclin B/CDK1 and TRKA, respectively.

HY-NP077A

Phaseolus vulgaris Lectin-P	Biochemical Assay Reagents	Inflammation/Immunology
Phaseolus vulgaris Lectin-P is the protein form of Phytohemagglutinin before the separation and purification of Phytohemagglutinin-L (PHA-L) and PHA-E. Phaseolus vulgaris Lectin-P can be used to stimulate the proliferation of peripheral mononuclear cells, promote the production of certain cytokines and the expression of membrane surface proteins .

HY-P10048

TAT-JIP	JNK	Inflammation/Immunology
TAT-JIP inhibits the phosphorylation of endogenous c-jun activated by PHA–PMA .

HY-10179R

Danusertib (Standard) PHA-739358 (Standard)	Reference Standards Aurora Kinase Autophagy	Cancer
Danusertib (Standard) is the analytical standard of Danusertib. This product is intended for research and analytical applications. Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively.

HY-101687

Nosantine racemate NPT 15392 racemate	Interleukin Related	Inflammation/Immunology
Nosantine racemate is the racemate of Nosantine. Nosantine is an inducer of IL-2 or enhancer of IL-2 induction by phytohemagglutinin (PHA).

HY-RS07545

LBR Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LBR Human Pre-designed siRNA Set A contains three designed siRNAs for LBR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LBR Human Pre-designed siRNA Set A LBR Human Pre-designed siRNA Set A

HY-113004R

3-Hydroxyvaleric acid (Standard)	Endogenous Metabolite Reference Standards	Metabolic Disease
3-Hydroxyvaleric acid (Standard) is the analytical standard of 3-Hydroxyvaleric acid. This product is intended for research and analytical applications. 3-Hydroxyvaleric acid is a five-carbon ketone body byproduct that can undergo an anaplerotic reaction to replenish the intermediates of the tricarboxylic acid cycle. 3-Hydroxyvaleric acid is one of the important monomers for the synthesis of polyhydroxyalkanoates (PHA). PHA is a type of biodegradable plastic that is widely used in environmentally friendly packaging, disposable products, and medical materials .

HY-I0301R

D-(+)-Glucono-1,5-lactone (Standard) Gluconic acid lactone (Standard)	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS)	Others
D-(+)-Glucono-1,5-lactone (Standard) is the analytical standard of D-(+)-Glucono-1,5-lactone. This product is intended for research and analytical applications. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-I0301S

D-(+)-Glucono-1,5-lactone-1-13C Gluconic acid lactone-1-¹³C	Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species (ROS)	Others
D-(+)-Glucono-1,5-lactone-1- ¹³C is the ¹³C labeled D-(+)-Glucono-1,5-lactone. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activ .

HY-W768262

D-(+)-Glucono-1,5-lactone-13C6 Gluconic acid lactone-¹³C₆	Reactive Oxygen Species (ROS)	Others
D-(+)-Glucono-1,5-lactone- ¹³C₆ (Gluconic acid lactone- ¹³C₆) is the ¹³C-labeled D-(+)-Glucono-1,5-lactone (HY-I0301). D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-118848

A63162	Lipoxygenase Leukotriene Receptor	Inflammation/Immunology
A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA)-induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin (HY-N6687)-induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease .

Cat. No.	Product Name	Type

HY-NP0184

Phaseolus Vulgaris Leucoagglutinin (Biotinylated) PHA-L (Biotinylated)	Biochemical Assay Reagents
Phaseolus Vulgaris Leucoagglutinin (PHA-L) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Phaseolus Vulgaris Leucoagglutinin (PHA-L) Biotinylated is a biological material or organic compound that can be used in life science research .

HY-NP077

Phaseolus vulgaris leucoagglutinin PHA-L	Biochemical Assay Reagents
Phaseolus vulgaris leucoagglutinin (PHA-L) is a lectin, that can be extracted from red kidney beans (Phaseolus vulgaris). Phaseolus vulgaris leucoagglutinin can be used as an anterograde axonal tracer in neuroanatomical research to study the morphology of neurons, axons, and terminal structures in the nervous system .

HY-113058

3-Hydroxyoctanoic acid

Biochemical Assay Reagents

3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

HY-W010625

Lithium 2-hydroxypropanoate 35+ Cited Publications	Biochemical Assay Reagents
Lithium 2-hydroxypropanoate is a lithium salt. Lithium 2-hydroxypropanoate has immunomodulatory activity (slightly enhancing PHA (HY-N7038)-induced lymphocyte proliferation). Lithium 2-hydroxypropanoate can be used in antioxidant activity assays. Lithium 2-hydroxypropanoate can be used in the research of mental diseases .

HY-NP076

Phaseolus Vulgaris Erythroagglutinin PHA-E	Biochemical Assay Reagents
Phaseolus Vulgaris Erythroagglutinin (PHA-E) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Phaseolus Vulgaris Erythroagglutinin (PHA-E) is a biological material or organic compound that can be used in life science research .

HY-NP0140

Phaseolus Vulgaris Leucoagglutinin (Fluorescein) PHA-L (Fluorescein)	Biochemical Assay Reagents
Phaseolus Vulgaris Leucoagglutinin (PHA-L) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Phaseolus Vulgaris Leucoagglutinin (PHA-L) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-NP0183

Phaseolus Vulgaris Erythroagglutinin (Biotinylated) PHA-E (Biotinylated)	Biochemical Assay Reagents
Phaseolus Vulgaris Erythroagglutinin (PHA-E) Biotinylated is a biological material or organic compound that can be used in life science research .

HY-NP077A

Phaseolus vulgaris Lectin-P	Biochemical Assay Reagents
Phaseolus vulgaris Lectin-P is the protein form of Phytohemagglutinin before the separation and purification of Phytohemagglutinin-L (PHA-L) and PHA-E. Phaseolus vulgaris Lectin-P can be used to stimulate the proliferation of peripheral mononuclear cells, promote the production of certain cytokines and the expression of membrane surface proteins .

HY-NP0139

Phaseolus Vulgaris Erythroagglutinin (Fluorescein) PHA-E (Fluorescein)	Biochemical Assay Reagents
Phaseolus Vulgaris Erythroagglutinin (PHA-E) Fluorescein is a biological material or organic compound that can be used in life science research .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99837

Dafsolimab SPV-T3a	CD3	Infection
Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .

HY-P991566

KD6001	CTLA-4	Cancer
KD6001 is a humanized IgG1κ monoclonal antibody, targeting CTLA4. KD6001 significantly disrupts CTLA-4 interactions with CD80 (IC₅₀: 16 ng/mL) and CD86. KD6001 enhances IL-2 and IFNγ expression in PHA-activated human lymphocytes and exhibits potent antitumor effects. KD6001 effectively inhibits tumor growth in MC38, B16, and Hepa1-6 tumor mice model. KD6001 can be used for cancers research, such as advanced melanoma, hepatocellular carcinoma and liver cancer .

HY-P992053

Anti-CD11a Antibody (MHM24)	Integrin	Inflammation/Immunology
Anti-CD11a Antibody (MHM24) is a monoclonal antibody targeting murine CD11a. Anti-CD11a Antibody (MHM24) binds to high-affinity (open) and low-affinity (closed) conformations of the α_L subunit of LFA-1, and functionally blocks LFA-1-mediated interactions. Anti-CD11a Antibody (MHM24) blocks ICAM-1 binding to LFA-1-expressing cells. Anti-CD11a Antibody (MHM24) inhibits adhesion of high-affinity LFA-1-expressing cells to keratinocytes. Anti-CD11a Antibody (MHM24) inhibits PHA-induced lymphocyte proliferation. Anti-CD11a Antibody (MHM24) can be used for the research of inflammatory and autoimmune diseases. Recommend Isotype Controls: mouse IgG1 kappa, Isotype Control (HY-P99977) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7038

Phytohemagglutinin 5+ Cited Publications PHA-M	Structural Classification Natural Products Classification of Application Fields Leguminosae Glycine max (L.) merr Plants Inflammation/Immunology Disease Research Fields Source Classification	NF-κB COX Interleukin Related Reactive Oxygen Species (ROS)
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β .

HY-N7038A

Phytohemagglutinin P PHA-P	Natural Products Classification of Application Fields Leguminosae Glycine max (L.) merr Plants Inflammation/Immunology Disease Research Fields Source Classification	Others
Phytohemagglutinin P (PHA-P) is a mitogen known to selectively stimulate cells of hematogenous or lymphoid monocytic origin .

HY-113004

3-Hydroxyvaleric acid	Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
3-Hydroxyvaleric acid is a five-carbon ketone body byproduct that can undergo an anaplerotic reaction to replenish the intermediates of the tricarboxylic acid cycle. 3-Hydroxyvaleric acid is one of the important monomers for the synthesis of polyhydroxyalkanoates (PHA). PHA is a type of biodegradable plastic that is widely used in environmentally friendly packaging, disposable products, and medical materials .

HY-I0301

D-(+)-Glucono-1,5-lactone 1 Publications Verification Gluconic acid lactone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Saccharides Source Classification	Environmental Pollutants Endogenous Metabolite Reactive Oxygen Species (ROS)
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-113058

3-Hydroxyoctanoic acid	Microorganisms Source Classification	Endogenous Metabolite
3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

HY-N1196

Suberosin	Classification of Application Fields Coumarins Phenylpropanoids Umbelliferae Plants Pluchea indica (L.) Less. Inflammation/Immunology Disease Research Fields Source Classification	NF-κB
Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB .

HY-113004R

3-Hydroxyvaleric acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
3-Hydroxyvaleric acid (Standard) is the analytical standard of 3-Hydroxyvaleric acid. This product is intended for research and analytical applications. 3-Hydroxyvaleric acid is a five-carbon ketone body byproduct that can undergo an anaplerotic reaction to replenish the intermediates of the tricarboxylic acid cycle. 3-Hydroxyvaleric acid is one of the important monomers for the synthesis of polyhydroxyalkanoates (PHA). PHA is a type of biodegradable plastic that is widely used in environmentally friendly packaging, disposable products, and medical materials .

HY-I0301R

D-(+)-Glucono-1,5-lactone (Standard) Gluconic acid lactone (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Saccharides Source Classification	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS)
D-(+)-Glucono-1,5-lactone (Standard) is the analytical standard of D-(+)-Glucono-1,5-lactone. This product is intended for research and analytical applications. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-N17413

(-)-γ-Cuparenol	Schisandra sphenanthera Rehd. et Wils Structural Classification Terpenoids Sesquiterpenes Plants Schisandraceae Source Classification	Bacterial Na+/K+ ATPase NF-κB Nuclear Factor of activated T Cells (NFAT)
(-)-γ-Cuparenol is a sesquiterpene compound with an IC₅₀ of 23.6 μg/mL against porcine Na ⁺/K ⁺-ATPase. (-)-γ-Cuparenol reduces phytohemagglutinin (PHA)-induced activation of NF-AT and NF-κB in Jurkat cells. (-)-γ-Cuparenol inhibits the growth of Gram-positive bacteria and some Gram-negative bacteria. (-)-γ-Cuparenol exhibits weak inhibitory activity against Candida albicans. (-)-γ-Cuparenol is applicable for research related to immunoregulation, cardiovascular diseases and bacterial infections .

Cat. No.	Product Name	Chemical Structure

HY-I0301S

D-(+)-Glucono-1,5-lactone-1-13C
D-(+)-Glucono-1,5-lactone-1- ¹³C is the ¹³C labeled D-(+)-Glucono-1,5-lactone. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activ .

HY-W768262

D-(+)-Glucono-1,5-lactone-13C6
D-(+)-Glucono-1,5-lactone- ¹³C₆ (Gluconic acid lactone- ¹³C₆) is the ¹³C-labeled D-(+)-Glucono-1,5-lactone (HY-I0301). D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2)
Application:	IHC-P (2) ICC/IF (2) WB (2) FC (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83406

	Lamin B Receptor Antibody (YA3151) PHA; LMN2R; TDRD18; DHCR14B; LBR	WB, IHC-P, ICC/IF, FC	Human, Rat
	Lamin B Receptor Antibody (YA3151) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lamin B Receptor.

HY-P83406A

	Lamin B Receptor Antibody (YA3151)(PBS only) PHA; LMN2R; TDRD18; DHCR14B; LBR	WB, IHC-P, ICC/IF, FC	Human, Rat
	Lamin B Receptor Antibody (YA3151) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lamin B Receptor.

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