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  6. Phytohemagglutinin P

Phytohemagglutinin P (PHA-P) is a mitogen known to selectively stimulate cells of hematogenous or lymphoid monocytic origin.

For research use only. We do not sell to patients.

Phytohemagglutinin P Chemical Structure

Phytohemagglutinin P Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Phytohemagglutinin P:

Phytohemagglutinin P Related Antibodies

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Description

Phytohemagglutinin P (PHA-P) is a mitogen known to selectively stimulate cells of hematogenous or lymphoid monocytic origin[1].

In Vitro

Phytohemagglutinin-P (10 μg/ml; 24-48hous)-stimulated decidual CD8+ T lymphocytes produces high levels of both interferon gamma and interleukin (IL) 8, and low levels of granulocyte-macrophage colony-stimulating factor (CSF2), IL1B, IL2, IL6, IL10, IL12, and tumor necrosis factor; these did not vary with gestational age[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Phytohemagglutinin P Related Antibodies
In Vivo

Phytohemagglutinin-P (25 and 50 mg/kg; i.p.; daily for 15 days; male Sprague-Dawley rats) shows a decrease in longitudinal bone growth, in the number of chondrocytes, in the thickness of cartilage plate, in the metaphyseal mass of hard tissue, in the percentage of calcified cartilage core, and in the number of osteoblasts per mm of bone surface. Additionally, PHA-P increases the number of osteoclasts, the number of labeled osteoclastic nuclei, and the average number of nuclei per osteoclast[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance

Solid

Color

White to light yellow

SMILES

[Phytohemagglutinin P]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (Need ultrasonic and warming)

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (Infinity mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

COA (241 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phytohemagglutinin PPHA-POthersstimulatehematogenouslymphoidmonocyticCSF2interleukinInhibitorinhibitorinhibit

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