1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

D-(+)-Glucono-1,5-lactone (Synonyms: Gluconic acid lactone)

Cat. No.: HY-I0301 Purity: >98.0%
Handling Instructions

D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

For research use only. We do not sell to patients.

D-(+)-Glucono-1,5-lactone Chemical Structure

D-(+)-Glucono-1,5-lactone Chemical Structure

CAS No. : 90-80-2

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Estimated Time of Arrival: December 31
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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

D-(+)-Glucono-1,5-lactone is a lactone (cyclic ester) of D-gluconic acid. D-(+)-Glucono-1,5-lactone is commonly found in honey, fruit juices, personal lubricants, and wine. D-(+)-Glucono-1,5-lactone is neutral, but hydrolyses in water to gluconic acid which is acidic, adding a tangy taste to foods, though it has roughly a third of the sourness of citric acid. It is metabolized to glucose; one gram of D-(+)-Glucono-1,5-lactone yields roughly the same amount of metabolicenergy as one gram of sugar. Upon addition to water, GDL is partially hydrolysed to gluconic acid, with the balance between the lactone form and the acid form established as a chemical equilibrium. The rate of hydrolysis of D-(+)-Glucono-1,5-lactone is increased by heat and high pH[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.6136 mL 28.0678 mL 56.1356 mL
5 mM 1.1227 mL 5.6136 mL 11.2271 mL
10 mM 0.5614 mL 2.8068 mL 5.6136 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

178.14

Formula

C₆H₁₀O₆

CAS No.

90-80-2

SMILES

O=C1[[email protected]](O)[[email protected]@H](O)[[email protected]](O)[[email protected]@H](CO)O1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
D-(+)-Glucono-1,5-lactone
Cat. No.:
HY-I0301
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D-(+)-Glucono-1,5-lactone

Cat. No.: HY-I0301